User profiles for W.R. Bevan-Jones

William Bevan-Jones

Verified email at doctors.org.uk
Cited by 1857

18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy

…, RJ Borchert, S Sami, TE Cope, WR Bevan-Jones… - Brain, 2017 - academic.oup.com
The ability to assess the distribution and extent of tau pathology in Alzheimer’s disease and
progressive supranuclear palsy in vivo would help to develop biomarkers for these …

Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy

…, P Vazquez Rodriguez, WR Bevan-Jones… - Brain, 2018 - academic.oup.com
Alzheimer’s disease and progressive supranuclear palsy (PSP) represent neurodegenerative
tauopathies with predominantly cortical versus subcortical disease burden. In Alzheimer’s …

Neuroinflammation and functional connectivity in Alzheimer's disease: interactive influences on cognitive performance

…, PS Jones, WR Bevan-Jones… - Journal of …, 2019 - Soc Neuroscience
Neuroinflammation is a key part of the etio-pathogenesis of Alzheimer's disease (AD). We
tested the relationship between neuroinflammation and the disruption of functional …

Microglial activation and tau burden predict cognitive decline in Alzheimer's disease

…, T Rittman, E Mak, N Nicastro, WR Bevan-Jones… - Brain, 2020 - academic.oup.com
Tau pathology, neuroinflammation, and neurodegeneration are key aspects of Alzheimer’s
disease. Understanding whether these features predict cognitive decline, alone or in …

Early microglial activation and peripheral inflammation in dementia with Lewy bodies

…, R Arnold, P Vázquez Rodríguez, WR Bevan-Jones… - Brain, 2018 - academic.oup.com
Inflammation is increasingly recognized as part of the pathology of neurodegenerative
conditions such as Alzheimer’s disease and Parkinson’s disease, but its role in dementia with …

Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum

WR Bevan-Jones, TE Cope, PS Jones, SS Kaalund… - Brain, 2020 - academic.oup.com
The clinical syndromes of frontotemporal dementia are clinically and neuropathologically
heterogeneous, but processes such as neuroinflammation may be common across the disease …

[11C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy

…, YT Hong, KSJ Allinson, WR Bevan-Jones… - Neurology, 2018 - AAN Enterprises
Objective We tested whether in vivo neuroinflammation relates to the distinctive distributions
of pathology in Alzheimer disease (AD) and progressive supranuclear palsy (PSP). …

Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia

…, E Mak, KA Tsvetanov, T Rittman, WR Bevan-Jones… - Brain, 2023 - academic.oup.com
Frontotemporal dementia is clinically and neuropathologically heterogeneous, but
neuroinflammation, atrophy and cognitive impairment occur in all of its principal syndromes. Across …

[18F] AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia

WR Bevan-Jones, TE Cope, PS Jones… - Journal of Neurology …, 2018 - jnnp.bmj.com
… general linear models with t-tests for each region of interest, excluding extraparenchymal
regions, first comparing each patient to the control group, as a case series (cf Bevan Jones et …

[HTML][HTML] Dissociable effects of acute SSRI (escitalopram) on executive, learning and emotional functions in healthy humans

…, F Cormack, L Passamonti, WR Bevan-Jones… - …, 2018 - nature.com
Serotonin is implicated in multiple executive functions including goal-directed learning, cognitive
flexibility, response inhibition and emotional regulation. These functions are impaired in …