Obesity is one of the most serious public health challenges in the world. Obesity during early
life has been associated with an increased risk of neurodevelopmental disorders, including …

The Nedd4 family E3 ligases are key regulators of cell growth and proliferation and are often
misregulated in human cancers and other diseases. The ligase activities of Nedd4 E3s are …

HECT E3 ligases control the degradation and functioning of numerous oncogenic/tumor-suppressive
factors and signaling proteins, and their activities must be tightly regulated to …

Due to its superiority in suppressing hydrogen generation under severe accident conditions,
silicon carbide (SiC) has been regarded as one of the promising candidates among the …

Background We confirmed that the filaggrin gene mutation c.3321delA is associated with
atopic dermatitis in our previous genome wide association study of the Chinese Han population…

Background: Previous studies have shown that individuals with schizophrenia have a greater
risk for psoriasis than a typical person. This suggests that there might be a shared genetic …

Axial and lateral pressure loss in a 5 × 5 rod–bundle with a split-type mixing vane spacer
grid was experimentally measured using differential pressure transmitters at different sub-…

The Nedd4 family E3 ligases Itch and WWP1/2 play crucial roles in the regulation of cell
cycle progression and apoptosis and are closely correlated with cancer development and …

Experimental study of coherent structures in a narrow rectangular channel with 50 percent
single side entrance blockage was conducted by time-resolved particle image velocimetry (TR…

Quantitative analysis of human reposting patterns on social networking sites will provide helpful
insights into the tracking and management of information spreading and social contagion…