Cholinergic muscarinic 2 receptor (CHRM2) is implicated in memory and cognition, functions
impaired in many neuropsychiatric disorders. Wang et al. [Wang, JC, Hinrichs, AL, Stock, H.…

We examined 13 single nucleotide polymorphisms (SNPs) spanning the coding region of
the µ-opioid receptor gene (OPRM1), among 382 European Americans (EAs) affected with …

Studies suggest that a functional polymorphism of the brain-derived neurotrophic factor gene
(BDNF Val66Met) may mediate hippocampal-dependent cognitive functions. A few studies …

The alcohol dehydrogenase (ADH) family constitutes one of the key sets of enzymes
responsible for the oxidation of alcohol. The ADH4 gene, an important member of this family, is a …

The set of alcohol-metabolizing enzymes has considerable genetic and functional
complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde …

Background: Each gene in the chromosome 11q23 cluster of NCAM1, TTC12, ANKK1, and
DRD2 is functionally linked to dopamine in brain. Many association studies of DRD2 and …

There have been many conflicting reports concerning the association of the DRD2 locus
with alcohol dependence (AD). To investigate whether these findings could be reconciled by …

Previous studies using SAGE (the Study of Addiction: Genetics and Environment) and COGA
(the Collaborative Study on the Genetics of Alcoholism) genome-wide association study (…

Sex differences are observed in both epidemiological and clinical aspects of major depressive
disorder (MDD). The cortico-limbic-striatal neural system, including the prefrontal cortex, …

Discovered in the brains of multiple animal species, piRNAs may contribute to the pathogenesis
of neuropsychiatric illnesses. The present study aimed to identify brain piRNAs across …