Objective: Pharmacological treatment is considered indispensable to major depressive
disorder. In spite of this, a significant number of patients do not respond adequately to …

Objective: Selective serotonin reuptake inhibitors (SSRIs) are frequently used as a first
antidepressant for major depressive disorder but have response rates of 50% to 60% in …

Purpose: This study assessed the extent of refill nonadherence with antiepileptic drugs
(AEDs) and the potential association between AED nonadherence and health care costs in …

Background: Despite the availability of effective antidepressants, recurrence and relapse
rates for depression are high (up to 80%), treatment failures are common (40% to 60%), and …

Learn about a pioneering alternative to antipsychotic medication for schizophrenia! In
Schizophrenia: Innovations in Diagnosis and Treatment, Dr. Colin A. Ross—founder of the …

To demonstrate the clinical effectiveness of an antidepressant drug requires evidence
beyond short-and long-term efficacy, including a favourable adverse-effect profile and …

BACKGROUND:: Attention-deficit/hyperactivity disorder (ADHD) has a substantial negative
impact; however, within long-term follow-up studies, a proportion of patients do very well …

The goal of precision medicine (individually tailored treatments) is not being achieved for
neurobehavioural conditions such as psychiatric disorders. Traditional randomized clinical …

Shared decision making (SDM) is a model of interaction between doctors and patients in
which both actors contribute to the medical decision-making process. There is an …

It is increasingly recognised that major depressive disorder can be a chronic condition with
many patients experiencing recurrent episodes. Remission from a depressive episode …