Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis
DO Perkins, H Gu, K Boteva… - American journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: The duration of untreated psychosis may influence response to treatment,
reflecting a potentially malleable progressive pathological process. The authors reviewed …
reflecting a potentially malleable progressive pathological process. The authors reviewed …
Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia
The underlying neurobiology of emerging psychotic disorders is not well understood. While
there is evidence from structural imaging and other studies supporting the popular notion …
there is evidence from structural imaging and other studies supporting the popular notion …
The neurobiology of duration of untreated psychosis: a comprehensive review
Duration of untreated psychosis (DUP) is defined as the time from the onset of psychotic
symptoms until the first treatment. Studies have shown that longer DUP is associated with …
symptoms until the first treatment. Studies have shown that longer DUP is associated with …
Duration of untreated psychosis and its relationship to clinical outcome
RMG Norman, SW Lewis, M Marshall - The British journal of …, 2005 - cambridge.org
BackgroundA major reason for interest in early intervention for psychotic disorders is the
hypothesised relationship between longer duration of untreated psychosis (DUP) and …
hypothesised relationship between longer duration of untreated psychosis (DUP) and …
Totally tubular: the mystery behind function and origin of the brain ventricular system
LA Lowery, H Sive - Bioessays, 2009 - Wiley Online Library
A unique feature of the vertebrate brain is the ventricular system, a series of connected
cavities which are filled with cerebrospinal fluid (CSF) and surrounded by neuroepithelium …
cavities which are filled with cerebrospinal fluid (CSF) and surrounded by neuroepithelium …
Does active psychosis cause neurobiological pathology? A critical review of the neurotoxicity hypothesis
BR Rund - Psychological medicine, 2014 - cambridge.org
BackgroundSince the neurotoxicity hypothesis was launched in 1991, it has generated a
great deal of interest and given rise to several studies investigating the validity of the …
great deal of interest and given rise to several studies investigating the validity of the …
[HTML][HTML] Relationship between duration of untreated psychosis and intrinsic corticostriatal connectivity in patients with early phase schizophrenia
Patients with first-episode psychosis experience psychotic symptoms for a mean of up to 2
years prior to initiation of treatment, and long duration of untreated psychosis (DUP) is …
years prior to initiation of treatment, and long duration of untreated psychosis (DUP) is …
Minimal evidence that untreated psychosis damages brain structures: a systematic review
Introduction A longer duration of untreated psychosis (DUP) is associated with poor
outcomes in first-episode psychosis (FEP); however, it is unclear whether this is due to the …
outcomes in first-episode psychosis (FEP); however, it is unclear whether this is due to the …
Defining, operationalizing and measuring the duration of untreated psychosis: advances, limitations and future directions
MT Compton, T Carter, E Bergner… - Early Intervention in …, 2007 - Wiley Online Library
Objective: Substantial converging evidence from schizophrenia researchers indicates that
the duration of untreated psychosis (DUP) represents a modifiable predictor of outcome …
the duration of untreated psychosis (DUP) represents a modifiable predictor of outcome …
Incidental findings on brain MRI in patients with first-episode and chronic psychosis
Brain incidental findings (IFs) are unexpected brain abnormalities detected by a structural
magnetic resonance (MRI) examination. We conducted a study to assess whether brain IFs …
magnetic resonance (MRI) examination. We conducted a study to assess whether brain IFs …