Developing reliable, predictive animal models for complex psychiatric disorders, such as
schizophrenia, is essential to increase our understanding of the neurobiological basis of the …

Schizophrenia is a highly debilitating mental disorder that affects∼ 1% of the general
population, yet it continues to be poorly understood. Recent studies have identified …

Neurodevelopmental models of schizophrenia that identify longitudinal precursors of illness
have been of great heuristic importance focusing most etiologic research over the past two …

BACKGROUND: Schizophrenia and bipolar disorder are severe psychiatric diseases with
overlapping symptomatology. Widespread brain morphologic abnormalities, including …

During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

The DISC locus is located at the breakpoint of a balanced t (1; 11) chromosomal
translocation in a large and unique Scottish family. This translocation segregates in a highly …

This article summarizes the discussion from a breakout group at the National Institute of
Mental Health–Measurement and Treatment Research to Improve Cognition in …

The underlying neurobiology of emerging psychotic disorders is not well understood. While
there is evidence from structural imaging and other studies supporting the popular notion …

Mesoaccumbens dopamine (DA) is involved in the stress response. Although neural
mechanisms involved in stress are of paramount importance for both clinical and preclinical …

Very preterm birth (VPT;< 32 weeks of gestation) has been associated with an increased risk
to develop cognitive and socio-emotional problems, as well as with increased vulnerability …