Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry

HC So, CKL Chau, WT Chiu, KS Ho, CP Lo… - Nature …, 2017 - nature.com
Abstract Knowledge of psychiatric disease genetics has advanced rapidly during the past
decade with the advent of genome-wide association studies (GWAS). However, less …

Remission, response without remission, and nonresponse in major depressive disorder: impact on functioning

MH Trivedi, PK Corey-Lisle, Z Guo… - International clinical …, 2009 - journals.lww.com
Major depressive disorder (MDD) is associated with significant functional impairment. This
post-hoc analysis of data from two randomized trials assessed the impact of response status …

[HTML][HTML] Comparing the prevalence of polypharmacy and potential drug-drug interactions in nursing homes and in the community dwelling elderly of Emilia Romagna …

S Burato, L Leonardi, IC Antonazzo, E Raschi… - Frontiers in …, 2021 - frontiersin.org
Backround: We aimed at assessing the prevalence of polypharmacy and potential drug-drug
interactions (DDIs) with clinical relevance in elderly patient on Emilia Romagna area. Both …

Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for …

HC So, CKL Chau, A Lau, SY Wong… - Psychological Medicine, 2019 - cambridge.org
BackgroundDepression and anxiety disorders (AD) are the first and sixth leading causes of
disability worldwide. Despite their high prevalence and significant disability resulted, there …

Augmentation therapy with tandospirone citrate in vascular depression patients with mild cognitive impairment: a prospective randomized clinical trial

R Chen, Q Lin, J Wu, Y Lin, T Lin, W Wu, X Chen… - Journal of Psychiatric …, 2023 - Elsevier
Cognitive impairment is a prominent clinical manifestation of vascular depression (VaDep).
The current study aimed to assess the efficacy of tandospirone citrate in VaDep cases with …

The therapeutic contribution of music in music-assisted systematic desensitization for substance addiction treatment: A pilot study

V Stamou, R Clerveaux, L Stamou… - The Arts in …, 2017 - Elsevier
We previously reported that music-assisted systematic desensitization can counter-condition
substance-related cues and reduce the implicated craving responses, as well as improve …

One-Year Outcomes for Depression and Anxiety in SLE Patients

L Duca, NA Roman, P Ifteni, A Teodorescu - Biomedicines, 2024 - mdpi.com
Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) is a severe form of SLE involving
the nervous system, resulting in neurological and psychiatric symptoms. Although research …

A controlled study of the efficacy and safety of tandospirone citrate combined with escitalopram in the treatment of vascular depression: a pilot randomized controlled …

H Chen, Q Lin, T Lin, Y Lin, X Lin, R Chen, L Luo… - Journal of Psychiatric …, 2019 - Elsevier
Vascular depression can respond poorly to antidepressants. This study aimed to explore the
efficacy and safety of tandospirone plus escitalopram for treating vascular depression with …

[PDF][PDF] Neuropharmacological activity of the crude ethanolic extract of Syzygium aromaticum flowering bud

MM Hossain, TD Aka, MS Rahman… - … -Journal of Natural …, 2019 - academia.edu
Backgroud: Present study was designed to assess the possibility of invivo
neuropharmacological effects of the ethanolic extract of Syzygium aromaticum flowering …

When GWAS meets the Connectivity Map: drug repositioning for seven psychiatric disorders

HC So, CKL Chau, WT Chiu, KS Ho, CP Lo, SHY Yim… - bioRxiv, 2016 - biorxiv.org
Our knowledge of disease genetics has advanced rapidly during the past decade, with the
advent of high-throughput genotyping technologies such as genome-wide association …