One of the most consistent findings in the biology of depression is an altered activity of the
hypothalamic–pituitary–adrenal (HPA) axis. However, data concerning this issue have never …

In recent years, an extensive body of literature focused on the gut–brain axis and the
possible role played by the gut microbiota in modulating brain morphology and function from …

Health, Illness, and Optimal Aging: Biological and Psychosocial Perspectives, Third Edition
shows the continuity and advancements in our understanding of human life-span …

Both ageing and chronic stress are associated with altered brain plasticity, dysregulation of
the immune system, and an increased risk of developing brain disorders; all of which have …

The current literature on aging and ageism is summarized in support of a theoretical
perspective that includes both the biological and the psychosocial components of these …

Increased hypothalamic–pituitary–adrenal (HPA) activation, culminating in elevated
circulating cortisol levels is a fundamental response to stressors. In animals, this …

Dementia and depression are frequently comorbid among older adult patients. Depression
is related to cognitive decrement and can even represent the first signs of a …

The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer's disease
proposed that chronic exposure to GCs promotes hippocampal aging and AD. This …

Allostatic load represents the strain that chronic stress exerts on interconnected biological
systems. Associated algorithms are related to numerous deleterious physical outcomes in …

The cognitive processes involved in inhibitory control accuracy (IC) and interference
resolution speed (IR) or broadly–inhibition–are discussed in this review, and both are …