Polypharmacy among adults aged 65 years and older in the United States: 1988–2010

CJ Charlesworth, E Smit, DSH Lee… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Older adults frequently have several chronic health conditions which require
multiple medications. We illustrated trends in prescription medication use over 20 years in …

On the transdiagnostic nature of peripheral biomarkers in major psychiatric disorders: a systematic review

JV Pinto, TC Moulin, OB Amaral - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
The search for biomarkers has been a leading endeavor in biological psychiatry. To analyze
its evolution over the years, we performed a systematic review to evaluate (a) the most …

[HTML][HTML] Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish

G Bruni, P Lakhani, D Kokel - Frontiers in pharmacology, 2014 - frontiersin.org
Most neuroactive drugs were discovered through unexpected behavioral observations.
Systematic behavioral screening is inefficient in most model organisms. But, automated …

[HTML][HTML] Rates of detection of mood and anxiety disorders in primary care: a descriptive, cross-sectional study

M Vermani, M Marcus, MA Katzman - The primary care companion …, 2011 - psychiatrist.com
Objective: To determine the incidence of major depressive disorder, bipolar disorder, panic
disorder, social anxiety disorder, and generalized anxiety disorder and to assess their …

Targeted disruption of the voltage-dependent calcium channel α2/δ-1-subunit

GA Fuller-Bicer, G Varadi, SE Koch… - American Journal …, 2009 - journals.physiology.org
Cardiac L-type voltage-dependent Ca2+ channels are heteromultimeric polypeptide
complexes of α1-, α2/δ-, and β-subunits. The α2/δ-1-subunit possesses a stereoselective …

Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study

Y Solak, Z Biyik, H Atalay, A Gaipov, F Guney… - …, 2012 - Wiley Online Library
Aim: Pruritus is common in dialysis patients. Peripheral neuropathy is also prevalent in this
patient population. However, the role of neuropathy in the genesis of uraemic itch has not …

[HTML][HTML] The effects of a gentle yoga program on sleep, mood, and blood pressure in older women with restless legs syndrome (RLS): a preliminary randomized …

KE Innes, TK Selfe - Evidence-Based Complementary and …, 2012 - hindawi.com
Objective. To examine the effects of yoga versus an educational film program on sleep,
mood, perceived stress, and sympathetic activation in older women with RLS. Methods …

[HTML][HTML] Temporal trends in antidepressant prescribing to children in UK primary care, 2000–2015

J Sarginson, RT Webb, SJ Stocks, A Esmail… - Journal of affective …, 2017 - Elsevier
Background The prevalence of antidepressant prescribing in children and adolescents
increased steadily in the United States and parts of Europe between 2005 and 2012 despite …

Nutrient-based therapies for bipolar disorder: a systematic review

LG Sylvia, AT Peters, T Deckersbach… - Psychotherapy and …, 2012 - karger.com
Background: Pharmacotherapy is the first line of treatment for bipolar disorder, but many
patients continue to experience persistent subthreshold symptoms. Alternative adjunct …

Benzodiazepine prescription for patients in opioid maintenance treatment in Norway

JG Bramness, H Kornør - Drug and alcohol dependence, 2007 - Elsevier
BACKGROUND: Opioid maintained patients report high levels of anxiety, but the use of
benzodiazepines among these patients has been associated with negative outcomes such …