Polypharmacy among adults aged 65 years and older in the United States: 1988–2010
CJ Charlesworth, E Smit, DSH Lee… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Older adults frequently have several chronic health conditions which require
multiple medications. We illustrated trends in prescription medication use over 20 years in …
multiple medications. We illustrated trends in prescription medication use over 20 years in …
On the transdiagnostic nature of peripheral biomarkers in major psychiatric disorders: a systematic review
The search for biomarkers has been a leading endeavor in biological psychiatry. To analyze
its evolution over the years, we performed a systematic review to evaluate (a) the most …
its evolution over the years, we performed a systematic review to evaluate (a) the most …
[HTML][HTML] Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish
G Bruni, P Lakhani, D Kokel - Frontiers in pharmacology, 2014 - frontiersin.org
Most neuroactive drugs were discovered through unexpected behavioral observations.
Systematic behavioral screening is inefficient in most model organisms. But, automated …
Systematic behavioral screening is inefficient in most model organisms. But, automated …
[HTML][HTML] Rates of detection of mood and anxiety disorders in primary care: a descriptive, cross-sectional study
M Vermani, M Marcus, MA Katzman - The primary care companion …, 2011 - psychiatrist.com
Objective: To determine the incidence of major depressive disorder, bipolar disorder, panic
disorder, social anxiety disorder, and generalized anxiety disorder and to assess their …
disorder, social anxiety disorder, and generalized anxiety disorder and to assess their …
Targeted disruption of the voltage-dependent calcium channel α2/δ-1-subunit
GA Fuller-Bicer, G Varadi, SE Koch… - American Journal …, 2009 - journals.physiology.org
Cardiac L-type voltage-dependent Ca2+ channels are heteromultimeric polypeptide
complexes of α1-, α2/δ-, and β-subunits. The α2/δ-1-subunit possesses a stereoselective …
complexes of α1-, α2/δ-, and β-subunits. The α2/δ-1-subunit possesses a stereoselective …
Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study
Y Solak, Z Biyik, H Atalay, A Gaipov, F Guney… - …, 2012 - Wiley Online Library
Aim: Pruritus is common in dialysis patients. Peripheral neuropathy is also prevalent in this
patient population. However, the role of neuropathy in the genesis of uraemic itch has not …
patient population. However, the role of neuropathy in the genesis of uraemic itch has not …
[HTML][HTML] The effects of a gentle yoga program on sleep, mood, and blood pressure in older women with restless legs syndrome (RLS): a preliminary randomized …
Objective. To examine the effects of yoga versus an educational film program on sleep,
mood, perceived stress, and sympathetic activation in older women with RLS. Methods …
mood, perceived stress, and sympathetic activation in older women with RLS. Methods …
[HTML][HTML] Temporal trends in antidepressant prescribing to children in UK primary care, 2000–2015
Background The prevalence of antidepressant prescribing in children and adolescents
increased steadily in the United States and parts of Europe between 2005 and 2012 despite …
increased steadily in the United States and parts of Europe between 2005 and 2012 despite …
Nutrient-based therapies for bipolar disorder: a systematic review
LG Sylvia, AT Peters, T Deckersbach… - Psychotherapy and …, 2012 - karger.com
Background: Pharmacotherapy is the first line of treatment for bipolar disorder, but many
patients continue to experience persistent subthreshold symptoms. Alternative adjunct …
patients continue to experience persistent subthreshold symptoms. Alternative adjunct …
Benzodiazepine prescription for patients in opioid maintenance treatment in Norway
JG Bramness, H Kornør - Drug and alcohol dependence, 2007 - Elsevier
BACKGROUND: Opioid maintained patients report high levels of anxiety, but the use of
benzodiazepines among these patients has been associated with negative outcomes such …
benzodiazepines among these patients has been associated with negative outcomes such …