Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

F Ng, M Berk, O Dean, AI Bush - International Journal of …, 2008 - academic.oup.com
Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

Potential mechanisms of action of lithium in bipolar disorder: Current understanding

GS Malhi, M Tanious, P Das, CM Coulston, M Berk - CNS drugs, 2013 - Springer
Lithium has been used for over half a century for the treatment of bipolar disorder as the
archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in …

Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress

G Patki, N Solanki, F Atrooz, F Allam, S Salim - Brain research, 2013 - Elsevier
In the present study, we have examined the behavioral and biochemical effect of induction of
psychological stress using a modified version of the resident-intruder model for social stress …

Allostatic load in bipolar disorder: implications for pathophysiology and treatment

F Kapczinski, E Vieta, AC Andreazza, BN Frey… - Neuroscience & …, 2008 - Elsevier
Current literature on the effects of chronic stress in general health converges to the concept
of allostatic load (AL). AL is the bodily 'wear and tear'that emerges with sustained allostatic …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Research in people with psychosis risk syndrome: a review of the current evidence and future directions

CU Correll, M Hauser, AM Auther… - Journal of Child …, 2010 - Wiley Online Library
After decades of research, schizophrenia and related psychotic disorders are still among the
most debilitating disorders in medicine. The chronic illness course in most individuals …

Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants

SY Lee, SJ Lee, C Han, AA Patkar, PS Masand… - Progress in Neuro …, 2013 - Elsevier
The brain is an organ predisposed to oxidative/nitrosative stress. This is especially true in
the case of aging as well as several neurodegenerative diseases. Under such …

Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia

M Kunz, CS Gama, AC Andreazza, M Salvador… - Progress in Neuro …, 2008 - Elsevier
There is an increasing body of evidence suggesting that oxidative stress may play a role in
the pathophysiology of both schizophrenia (SZ) and bipolar disorder (BD). METHODS: We …

Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection

B Monti, E Polazzi… - Current molecular …, 2009 - ingentaconnect.com
Valproic acid (VPA, 2-propylpentanoic acid) has been widely used as an antiepileptic drug
and for the therapy of bipolar disorders for several years. Its mechanism of action was …