Pathophysiological mechanisms implicated in postpartum depression
This review aims to summarize the diverse proposed pathophysiological mechanisms
contributing to postpartum depression, highlighting both clinical and basic science research …
contributing to postpartum depression, highlighting both clinical and basic science research …
Revisiting the serotonin hypothesis: implications for major depressive disorders
M Fakhoury - Molecular neurobiology, 2016 - Springer
Major depressive disorder (MDD) is a heritable neuropsychiatric disease associated with
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …
Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms
C Andrade, S Sandarsh, KB Chethan… - Journal of Clinical …, 2010 - psychiatrist.com
Background: It is generally believed that selective serotonin reuptake inhibitor (SSRI) drugs
increase the risk of abnormal bleeding and decrease the risk of ischemic heart disease …
increase the risk of abnormal bleeding and decrease the risk of ischemic heart disease …
Identification and management of peripartum depression
RC Langan, AJ Goodbred - American family physician, 2016 - aafp.org
Peripartum depression affects up to one in seven women and is associated with significant
maternal and neonatal morbidity if untreated. A history of depression is the strongest risk …
maternal and neonatal morbidity if untreated. A history of depression is the strongest risk …
Diagnosis, pathophysiology, and management of mood disorders in pregnant and postpartum women
KA Yonkers, S Vigod, LE Ross - Obstetrics & Gynecology, 2011 - journals.lww.com
Mood disorders disproportionately affect women across the lifespan. Mood disorders in
pregnancy and the postpartum period are common and have profound implications for …
pregnancy and the postpartum period are common and have profound implications for …
Anxiety disorders: sex differences in serotonin and tryptophan metabolism
T Songtachalert, C Roomruangwong… - Current topics in …, 2018 - ingentaconnect.com
Introduction: Anxiety disorders manifest in women more than in men by almost twofold. This
narrative review aims to summarize the sex-related biological factors, which underpin …
narrative review aims to summarize the sex-related biological factors, which underpin …
Biological aspects of postpartum depression
A Skalkidou, C Hellgren, E Comasco… - Women's …, 2012 - journals.sagepub.com
In comparison with the vast epidemiological literature on postpartum depression (PPD),
relatively few studies have examined the biological aspects of the disorder. However …
relatively few studies have examined the biological aspects of the disorder. However …
Serotonin and motherhood: From molecules to mood
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin,
in the display of maternal behaviors and reproduction-associated plasticity in the maternal …
in the display of maternal behaviors and reproduction-associated plasticity in the maternal …
Potential role of neuroactive tryptophan metabolites in central fatigue: establishment of the fatigue circuit
M Yamashita - International Journal of Tryptophan Research, 2020 - journals.sagepub.com
Central fatigue leads to reduced ability to perform mental tasks, disrupted social life, and
impaired brain functions from childhood to old age. Regarding the neurochemical …
impaired brain functions from childhood to old age. Regarding the neurochemical …
Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid …
DS Reddy, RH Mbilinyi, E Estes - Psychopharmacology, 2023 - Springer
This article describes the critical role of neurosteroids in postpartum depression (PPD) and
outlines the landmark pharmacological journey of brexanolone as a first-in-class …
outlines the landmark pharmacological journey of brexanolone as a first-in-class …