[HTML][HTML] The serotonin theory of depression: a systematic umbrella review of the evidence
J Moncrieff, RE Cooper, T Stockmann… - Molecular …, 2023 - nature.com
The serotonin hypothesis of depression is still influential. We aimed to synthesise and
evaluate evidence on whether depression is associated with lowered serotonin …
evaluate evidence on whether depression is associated with lowered serotonin …
[HTML][HTML] Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017
C Hiemke, N Bergemann, HW Clement… - …, 2018 - thieme-connect.com
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
Neural mechanisms of the cognitive model of depression
In the 40 years since Aaron Beck first proposed his cognitive model of depression, the
elements of this model—biased attention, biased processing, biased thoughts and …
elements of this model—biased attention, biased processing, biased thoughts and …
[HTML][HTML] AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011
Therapeutic drug monitoring (TDM), ie, the quantification of serum or plasma concentrations
of medications for dose optimization, has proven a valuable tool for the patient-matched …
of medications for dose optimization, has proven a valuable tool for the patient-matched …
SLC6 neurotransmitter transporters: structure, function, and regulation
AS Kristensen, J Andersen, TN Jørgensen… - Pharmacological …, 2011 - ASPET
The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
[HTML][HTML] A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression
A recent “umbrella” review examined various biomarkers relating to the serotonin system,
and concluded there was no consistent evidence implicating serotonin in the …
and concluded there was no consistent evidence implicating serotonin in the …
[PDF][PDF] Neurobiology of depression, fibromyalgia and neuropathic pain
V Raison - Front Biosci, 2009 - researchgate.net
[Frontiers in Bioscience 14, 5291-5338, June 1, 2009] 5291 Neurobiology of depression,
fibromyalgia and neuropathic pain Vladimi Page 1 [Frontiers in Bioscience 14, 5291-5338, June …
fibromyalgia and neuropathic pain Vladimi Page 1 [Frontiers in Bioscience 14, 5291-5338, June …
Revisiting the serotonin hypothesis: implications for major depressive disorders
M Fakhoury - Molecular neurobiology, 2016 - Springer
Major depressive disorder (MDD) is a heritable neuropsychiatric disease associated with
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …
severe changes at cellular and molecular levels. Its diagnosis mainly relies on the …
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder
A Mørk, A Pehrson, LT Brennum, SM Nielsen… - … of Pharmacology and …, 2012 - ASPET
1-[2-(2, 4-Dimethylphenyl-sulfanyl)-phenyl]-piperazine (Lu AA21004) is a human (h)
serotonin (5-HT) 3A receptor antagonist (Ki= 3.7 nM), h5-HT7 receptor antagonist (K i= 19 …
serotonin (5-HT) 3A receptor antagonist (Ki= 3.7 nM), h5-HT7 receptor antagonist (K i= 19 …
Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease
SJ Kish, J Tong, O Hornykiewicz, A Rajput, LJ Chang… - Brain, 2008 - academic.oup.com
Interest in serotonergic involvement in Parkinson's disease (PD) has focussed recently on
the possibility that the remaining serotonin neurons innervating striatum (caudate and …
the possibility that the remaining serotonin neurons innervating striatum (caudate and …