Objective: Suicide, a major cause of death worldwide, has distinct biological underpinnings.
The authors review and synthesize the research literature on biomarkers of suicide, with the …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Objective: To address issues concerning potential treatment-emergent “suicidality,” a
consensus conference was convened March 23-24, 2009. Participants: This gathering of …

Major depressive disorder (MDD) is a leading cause of disability worldwide and results
tragically in the loss of almost one million lives in Western societies every year. This is due to …

Bipolar disorder (BD) is a major medical and social burden, whose cause, pathophysiology
and treatment are not agreed on. It is characterized by recurrent periods of mania and …

Accumulating translational evidence suggests that the long-chain omega-3 fatty acid
docosahexaenoic acid (DHA) plays a role in the maturation and stability of cortical circuits …

Converging translational evidence has implicated elevated immune-inflammatory signaling
activity in the pathoetiology of mood disorders, including major depressive disorder and …

A body of evidence has implicated dietary deficiency in omega-3 polyunsaturated fatty acids
(n-3 PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in …