Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

Reduced capacity to cognitively regulate emotional responses is a common impairment
across major neuropsychiatric disorders. Brain systems supporting one such strategy …

Obsessive–compulsive disorder (OCD) is a highly prevalent and chronic condition that is
associated with substantial global disability. OCD is the key example of the 'obsessive …

Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Obsessive compulsive disorder is prevalent, disabling, incompletely understood, and often
resistant to current therapies. Established treatments consist of specialized cognitive …

Obsessive–compulsive disorder (OCD) was previously considered refractory to most types
of therapeutic intervention. There is now, however, ample evidence that selective serotonin …

Background Error processing and inhibitory control enable the adjustment of behaviors to
meet task demands. Functional magnetic resonance imaging studies report brain activation …

Objective: The purpose of this study was to determine the neural correlates of excessive
habit formation in obsessive-compulsive disorder (OCD). The authors aimed to test for …

Background Patients with obsessive-compulsive disorder (OCD) experience aversive
emotions in response to obsessions, motivating avoidance and compulsive behaviors …

Background Obsessive-compulsive disorder (OCD) is associated with regional hyperactivity
in cortico-striatal circuits. However, the large-scale patterns of abnormal neural connectivity …