Brain-derived neurotrophic factor (BDNF) regulates the survival and growth of neurons, and
influences synaptic efficiency and plasticity. Several studies report reduced peripheral …

Lithium has been and continues to be the mainstay of bipolar disorder (BD)
pharmacotherapy for acute mood episodes, switch prevention, prophylactic treatment, and …

Arginine vasopressin (AVP) and oxytocin (OXT) are social hormones and mediate affiliative
behaviors in mammals and as recently demonstrated, also in humans. There is intense …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Bipolar disorder (BD) and major depressive disorder (MDD) are major psychiatric disorders
and a diagnostic challenge during depressive episodes. Noteworthy, the proper …

Several studies have suggested an important role for brain-derived neurotrophic factor
(BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms …

Evidence has suggested a role of brain-derived neurotrophic factor (BDNF) in the
pathogenesis of bipolar disorder (BD). Recent studies have examined BDNF levels in BD …

Bipolar disorder (BD) is a chronic psychiatric illness of which the pathophysiology remains
partially unknown. Abnormalities of neurotrophins and other trophic factors orchestrate …

Background There is an emerging interest in the use of cellular models to study psychiatric
disorders. We have systematically reviewed the application of cellular models to understand …

Mitochondrial dysfunction, oxidative stress, and alterations in DNA methylation, are all
associated with the pathophysiology of bipolar disorder (BD). We therefore studied the …