Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

[HTML][HTML] Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

Problems with measuring peripheral oxytocin: can the data on oxytocin and human behavior be trusted?

ME McCullough, PS Churchland, AJ Mendez - … & Biobehavioral Reviews, 2013 - Elsevier
Research on the neurobiological and behavioral effects of oxytocin (OT), as well as on its
possible therapeutic applications, has intensified in the past decade. Accurate determination …

Does oxytocin increase trust in humans? A critical review of research

G Nave, C Camerer… - … on Psychological Science, 2015 - journals.sagepub.com
Behavioral neuroscientists have shown that the neuropeptide oxytocin (OT) plays a key role
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …

Evaluation of enzyme immunoassay and radioimmunoassay methods for the measurement of plasma oxytocin

A Szeto, PM McCabe, DA Nation, BA Tabak… - Psychosomatic …, 2011 - journals.lww.com
Objective: There is increased interest in measuring peripheral oxytocin levels to better
understand the role of this peptide in mammalian behavior, physiology, and disease. The …

[HTML][HTML] Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders

K Skorobogatov, L De Picker, R Verkerk… - Frontiers in …, 2021 - frontiersin.org
Objective Disturbances in the kynurenine pathway have been implicated in the
pathophysiology of psychotic and mood disorders, as well as several other psychiatric …

Plasma oxytocin and vasopressin do not predict neuropeptide concentrations in human cerebrospinal fluid

SM Kagerbauer, J Martin, T Schuster… - Journal of …, 2013 - Wiley Online Library
The involvement of the neuropeptides oxytocin (OXT) and vasopressin (AVP) in human
socio‐emotional behaviours is attracting increasing attention. There is ample evidence for …

[HTML][HTML] Dissecting the role of oxytocin in the formation and loss of social relationships

R Hurlemann, D Scheele - Biological Psychiatry, 2016 - Elsevier
Current concepts of human sociality highlight a fundamental role of the hypothalamic
peptide oxytocin (OXT) in the formation and maintenance of social relationships. However …

[HTML][HTML] Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders

K Macdonald, D Feifel - Frontiers in neuroscience, 2013 - frontiersin.org
Concerns regarding a drought in psychopharmacology have risen from many quarters. From
one perspective, the wellspring of bedrock medications for anxiety disorders, depression …

Oxytocin׳ s role in anxiety: A critical appraisal

K MacDonald, D Feifel - Brain research, 2014 - Elsevier
A growing literature suggests that the oxytocin (OT) system may play a role in human anxiety
states, anxiety-related traits, and moreover, that this system may be a target for the …