Objective Schizophrenia results in cognitive impairments as well as positive, negative, and
disorganized symptomatology. The present study examines the extent to which these …

The insular cortex is one of the brain regions that show consistent abnormalities in both
structural and functional neuroimaging studies of schizophrenia. In healthy individuals, the …

Research traditions on cognition and depression focus on relatively unconnected aspects of
cognitive functioning. On one hand, the neuropsychological perspective has concentrated …

Executive functioning (EF) is an important cognitive domain that is negatively affected in a
number of neuropsychiatric conditions. Neuroimaging methods have led to insights into the …

Schizophrenia is a chronic and debilitating mental illness characterized by a broad range of
abnormal behaviors, including delusions and hallucinations, impaired cognitive function, as …

The glutamate hypothesis of schizophrenia, proposed over two decades ago, originated
following the observation that administration of drugs that block NMDA glutamate receptors …

BackgroundSalience network (SN) dysconnectivity has been hypothesized to contribute to
schizophrenia. Nevertheless, little is known about the functional and structural …

BACKGROUND & AIMS: Patients with irritable bowel syndrome (IBS) have increased activity
in the insula and reduced activation of the dorsolateral prefrontal cortex (DLPFC) in …

Attentional set-shifting, as a measure of executive flexibility, has been a staple of
investigations into human cognition for over six decades. Mediated by the frontal cortex in …

Previous studies suggested that the topological properties of brain anatomical networks may
be aberrant in schizophrenia (SCZ), and most of them focused on the chronic and …