Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …

Glutathione (GSH) is a tripeptide, which has many biological roles including protection
against reactive oxygen and nitrogen species. The primary goal of this paper is to …

Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases,
inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress …

Abstract N-acetyl-l-cysteine (NAC) has long been used therapeutically for the treatment of
acetaminophen (paracetamol) overdose, acting as a precursor for the substrate (l-cysteine) …

Objective. To review the clinical usefulness of N-acetylcysteine (NAC) as treatment or
adjunctive therapy in a number of medical conditions. Use in Tylenol overdose, cystic …

Since the introduction of chlorpromazine and throughout the development of the new-
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …

N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of
multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant …

Background There is an expanding field of research investigating the benefits of medicines
with multiple mechanisms of action across neurological disorders. N‐acetylcysteine (NAC) …