Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …

Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

Mounting evidence shows that the complex gut microbial ecosystem in the human
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …

An interaction between external stressors and intrinsic vulnerability is one of the longest
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …

Synapses are the site for brain communication where information is transmitted between
neurons and stored for memory formation. Synaptic degeneration is a global and early …

The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …

The assembly of functional neural circuits requires the combined action of progressive and
regressive events. Regressive events encompass a variety of inhibitory developmental …

A scanning electron microscope (SEM) provides real-time imaging with nanometer
resolution and a large scanning area, which enables the development and integration of …

Schizophrenia is a severe and clinically heterogenous mental disorder affecting
approximately 1% of the population worldwide. Despite tremendous achievements in the …

The prenatal and early postnatal stages represent a critical time window for human brain
development. Interestingly, this window partly overlaps with the maturation of the intestinal …