A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research

ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - Am Psychiatric Assoc
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Contrasting variability patterns in the default mode and sensorimotor networks balance in bipolar depression and mania

M Martino, P Magioncalda, Z Huang… - Proceedings of the …, 2016 - National Acad Sciences
Depressive and manic phases in bipolar disorder show opposite constellations of affective,
cognitive, and psychomotor symptoms. At a neural level, these may be related to …

Decreased amygdala–insula resting state connectivity in behaviorally and emotionally dysregulated youth

G Bebko, M Bertocci, H Chase, A Dwojak… - Psychiatry Research …, 2015 - Elsevier
Abstract The Research Domain Criteria (RDoC) adopts a dimensional approach for
examining pathophysiological processes underlying categorically defined psychiatric …

Early signs of anomalous neural functional connectivity in healthy offspring of parents with bipolar disorder

MK Singh, KD Chang, RG Kelley, M Saggar… - Bipolar …, 2014 - Wiley Online Library
Objectives Bipolar disorder (BD) has been associated with dysfunctional brain connectivity
and with family chaos. It is not known whether aberrant connectivity occurs before illness …

Aberrant resting-state functional connectivity in the default mode network in pediatric bipolar disorder patients with and without psychotic symptoms

Y Zhong, C Wang, W Gao, Q Xiao, D Lu, Q Jiao… - Neuroscience …, 2019 - Springer
Mood disorders/psychosis have been associated with dysfunctions in the default mode
network (DMN). However, the relative contributions of DMN regions to state and trait …

Aberrant amygdala intrinsic functional connectivity distinguishes youths with bipolar disorder from those with severe mood dysregulation

J Stoddard, D Hsu, RC Reynolds, MA Brotman… - Psychiatry Research …, 2015 - Elsevier
It remains unclear the degree to which youths with episodic mania (bipolar disorder; BD) vs.
those with chronic, severe irritability (severe mood dysregulation, SMD) should be placed in …

[HTML][HTML] Abnormal degree centrality associated with cognitive dysfunctions in early bipolar disorder

W Deng, B Zhang, W Zou, X Zhang, X Cheng… - Frontiers in …, 2019 - frontiersin.org
Delayed diagnosis of bipolar disorder (BD) is common. However, diagnostic validity may be
enhanced using reliable neurobiological markers for BD. Degree centrality (DC) is one such …

Global and local cortical folding alterations are associated with neurodevelopmental subtype in bipolar disorders: a sulcal pits analysis

A Lefrere, G Auzias, P Favre, I Kaltenmark… - Journal of Affective …, 2023 - Elsevier
Background Analyzing cortical folding may provide insight into the biological underpinnings
of neurodevelopmental diseases. A neurodevelopmental subtype of bipolar disorders (BD …

Aberrant intrinsic functional connectivity within and between corticostriatal and temporal–parietal networks in adults and youth with bipolar disorder

J Stoddard, SJ Gotts, MA Brotman, S Lever… - Psychological …, 2016 - cambridge.org
BackgroundMajor questions remain regarding the dysfunctional neural circuitry underlying
the pathophysiology of bipolar disorder (BD) in both youths and adults. In both age groups …

[PDF][PDF] I feel, therefore, I am: the insula and its role in human emotion, cognition and the sensory-motor system.

M Pavuluri, A May - Aims Neuroscience, 2015 - aimspress.com
Background: The insula is instrumental in integrating the emotional, cognitive, and sensory-
motor systems. This manuscript lays a foundational framework for understanding the insula's …