Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

MP Dandekar, AJ Fenoy, AF Carvalho, JC Soares… - Molecular …, 2018 - nature.com
Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

[HTML][HTML] Deep brain stimulation for depression

M Figee, P Riva-Posse, KS Choi, L Bederson… - …, 2022 - Elsevier
Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial

PE Holtzheimer, MM Husain, SH Lisanby… - The Lancet …, 2017 - thelancet.com
Background Deep brain stimulation (DBS) of the subcallosal cingulate white matter has
shown promise as an intervention for patients with chronic, unremitting depression. To test …

A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression

P Riva-Posse, KS Choi, PE Holtzheimer… - Molecular …, 2018 - nature.com
Target identification and contact selection are known contributors to variability in efficacy
across different clinical indications of deep brain stimulation surgery. A retrospective …

Cingulate dynamics track depression recovery with deep brain stimulation

S Alagapan, KS Choi, S Heisig, P Riva-Posse… - Nature, 2023 - nature.com
Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) can provide long-term
symptom relief for treatment-resistant depression (TRD). However, achieving stable recovery …

Defining critical white matter pathways mediating successful subcallosal cingulate deep brain stimulation for treatment-resistant depression

P Riva-Posse, KS Choi, PE Holtzheimer, CC McIntyre… - Biological …, 2014 - Elsevier
Background Subcallosal cingulate white matter (SCC) deep brain stimulation (DBS) is an
evolving investigational treatment for depression. Mechanisms of action are hypothesized to …

Long-term outcomes of subcallosal cingulate deep brain stimulation for treatment-resistant depression

AL Crowell, P Riva-Posse… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Deep brain stimulation of the subcallosal cingulate (SCC DBS) has been studied
as a potential treatment for severe and refractory major depressive disorder since 2005. The …

[HTML][HTML] Deep brain stimulation targets for treating depression

D Drobisz, A Damborská - Behavioural brain research, 2019 - Elsevier
Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …

A systematic review and meta‐analysis of deep brain stimulation for depression

S Kisely, A Li, N Warren, D Siskind - Depression and anxiety, 2018 - Wiley Online Library
Background Deep brain stimulation is increasingly being used for treatment‐resistant
depression. Blinded, randomized controlled trials of active versus sham treatment have …

[HTML][HTML] Dosing of electrical parameters in deep brain stimulation (DBS) for intractable depression: a review of clinical studies

R Ramasubbu, S Lang, ZHT Kiss - Frontiers in psychiatry, 2018 - frontiersin.org
Background: The electrical parameters used for deep brain stimulation (DBS) in movement
disorders have been relatively well studied, however for the newer indications of DBS for …