Precision medicine is increasingly recognized as a promising approach to improve disease
treatment, taking into consideration the individual clinical and biological characteristics …

Electroconvulsive therapy (ECT), developed in the 30′ s by Bini and Cerletti, remains a key
element of the therapeutic armamentarium in psychiatry, particularly for severe and life …

Objective To compare characteristics of bipolar disorder patients diagnosed as DSM-5 types
I (BD-1) vs. II (BD-2). Methods We compared descriptive, psychopathological, and treatment …

Introduction: Bipolar disorder (BD) is a chronic psychiatric disorder marked by clinical and
pathophysiological heterogeneity. There is a high expectation that personalized approaches …

Currently becoming widely recognized, personalized psychiatry focuses on unique
physiological and genetic profiles of patients to best tailor their therapy. However, the role of …

Depression is a wide-spread, debilitating psychiatric disorder. Mainly rodent-based,
experimental animal models of depression are extensively used to probe the pathogenesis …

A personalized medicine approach seems to be particularly applicable to psychiatry. Indeed,
considering mental illness as deregulation, unique to each patient, of molecular pathways …

“Precision medicine” and “personalized medicine” constitute goals of research since
antiquity and this was intensified with the arrival of the “evidence-based medicine.” precision …

Abstract Treatment‑resistant schizophrenia (TRS) is a common phenotype of schizophrenia
that places a considerable burden on patients as well as on society. TRS is known for its …

Abstract Background Major Depressive Disorder and Generalized Anxiety Disorder are
pervasive and debilitating conditions, though treatment is often inaccessible and based on …