Gender differences in social anxiety disorder: A review

M Asher, A Asnaani, IM Aderka - Clinical psychology review, 2017 - Elsevier
Gender differences in social anxiety disorder (SAD) have not received much empirical
attention despite the large body of research on the disorder, and in contrast to significant …

Evaluation of the social motivation hypothesis of autism: a systematic review and meta-analysis

CC Clements, AR Zoltowski, LD Yankowitz… - JAMA …, 2018 - jamanetwork.com
Importance The social motivation hypothesis posits that individuals with autism spectrum
disorder (ASD) find social stimuli less rewarding than do people with neurotypical activity …

Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity

FB Spengler, J Schultz, D Scheele, M Essel, W Maier… - Biological …, 2017 - Elsevier
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay

MR Lee, KB Scheidweiler, XX Diao, F Akhlaghi… - Molecular …, 2018 - nature.com
Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …

[HTML][HTML] Social skills deficits in autism spectrum disorder: potential biological origins and progress in developing therapeutic agents

RE Frye - CNS drugs, 2018 - Springer
Autism spectrum disorder is defined by two core symptoms: a deficit in social communication
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …

[PDF][PDF] A cortical circuit for sexually dimorphic oxytocin-dependent anxiety behaviors

K Li, M Nakajima, I Ibañez-Tallon, N Heintz - Cell, 2016 - cell.com
The frequency of human social and emotional disorders varies significantly between males
and females. We have recently reported that oxytocin receptor interneurons (OxtrINs) …

[HTML][HTML] Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits

DA Baribeau, E Anagnostou - Frontiers in neuroscience, 2015 - frontiersin.org
Oxytocin and vasopressin are pituitary neuropeptides that have been shown to affect social
processes in mammals. There is growing interest in these molecules and their receptors as …

Oxytocin treatment, circuitry, and autism: a critical review of the literature placing oxytocin into the autism context

AJ Guastella, IB Hickie - Biological psychiatry, 2016 - Elsevier
Observed impairment in reciprocal social interaction is a diagnostic hallmark of autism
spectrum disorders. There is no effective medical treatment for these problems …

Oxytocin and pain perception: from animal models to human research

S Boll, ACA De Minas, A Raftogianni, SC Herpertz… - Neuroscience, 2018 - Elsevier
An accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin
(OT) has a modulatory effect on pain processing. Particularly strong evidence comes from …

Oxytocin and brain activity in humans: a systematic review and coordinate-based meta-analysis of functional MRI studies

SA Grace, SL Rossell, M Heinrichs… - …, 2018 - Elsevier
Oxytocin (OXT) is a neuropeptide which has a critical role in human social behaviour and
cognition. Research investigating the role of OXT on functional brain changes in humans …