Machine learning in major depression: From classification to treatment outcome prediction

S Gao, VD Calhoun, J Sui - CNS neuroscience & therapeutics, 2018 - Wiley Online Library
Aims Major depression disorder (MDD) is the single greatest cause of disability and
morbidity, and affects about 10% of the population worldwide. Currently, there are no …

Chronotype and circadian rhythm in bipolar disorder: a systematic review

MCA Melo, RLC Abreu, VBL Neto, PFC de Bruin… - Sleep medicine …, 2017 - Elsevier
Despite a complex relationship between mood, sleep and rhythm, the impact of circadian
disruptions on bipolar disorder (BD) has not been clarified. The purpose of this systematic …

[HTML][HTML] Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

DP Hibar, LT Westlye, NT Doan, N Jahanshad… - Molecular …, 2018 - nature.com
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

[HTML][HTML] Cortical thickness in major depressive disorder: A systematic review and meta-analysis

JS Suh, MA Schneider, L Minuzzi… - Progress in Neuro …, 2019 - Elsevier
Neuroimaging studies assessing neurobiological differences between patients with major
depressive disorder (MDD) and healthy controls (HC) are often hindered by small sample …

[HTML][HTML] Longitudinal structural brain changes in bipolar disorder: a multicenter neuroimaging study of 1232 individuals by the ENIGMA bipolar disorder working group

C Abé, CRK Ching, B Liberg, AV Lebedev, I Agartz… - Biological …, 2022 - Elsevier
Background Bipolar disorder (BD) is associated with cortical and subcortical structural brain
abnormalities. It is unclear whether such alterations progressively change over time, and …

[HTML][HTML] Mania-related effects on structural brain changes in bipolar disorder–a narrative review of the evidence

C Abé, B Liberg, AL Klahn, P Petrovic, M Landén - Molecular Psychiatry, 2023 - nature.com
Cross-sectional neuroimaging studies show that bipolar disorder is associated with
structural brain abnormalities, predominantly observed in prefrontal and temporal cortex …

Lithium as a neuroprotective agent for bipolar disorder: an overview

ELM Ochoa - Cellular and molecular neurobiology, 2022 - Springer
Lithium (Li+) is a first option treatment for adult acute episodes of Bipolar Disorder (BD) and
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …

Mood disorders in the elderly: prevalence, functional impact, and management challenges

LCL Valiengo, F Stella, OV Forlenza - … disease and treatment, 2016 - Taylor & Francis
Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

Shared and specific patterns of dynamic functional connectivity variability of striato-cortical circuitry in unmedicated bipolar and major depressive disorders

G Chen, P Chen, JY Gong, Y Jia, S Zhong… - Psychological …, 2022 - cambridge.org
Background Accumulating studies have found structural and functional abnormalities of the
striatum in bipolar disorder (BD) and major depressive disorder (MDD). However, changes …

Disrupted functional connectivity within the default mode network and salience network in unmedicated bipolar II disorder

JY Gong, G Chen, Y Jia, S Zhong, L Zhao, X Luo… - Progress in Neuro …, 2019 - Elsevier
Background Recent studies demonstrate that functional disruption in resting-state networks
contributes to cognitive and affective symptoms of bipolar disorder (BD), however, the …