Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder

E Shephard, ER Stern, OA van den Heuvel… - Molecular …, 2021 - nature.com
An important challenge in mental health research is to translate findings from cognitive
neuroscience and neuroimaging research into effective treatments that target the …

An overview of the first 5 years of the ENIGMA obsessive–compulsive disorder working group: The power of worldwide collaboration

OA Van den Heuvel, PSW Boedhoe… - Human brain …, 2022 - Wiley Online Library
Neuroimaging has played an important part in advancing our understanding of the
neurobiology of obsessive–compulsive disorder (OCD). At the same time, neuroimaging …

[HTML][HTML] A randomized trial directly comparing ventral capsule and anteromedial subthalamic nucleus stimulation in obsessive-compulsive disorder: clinical and …

H Tyagi, AM Apergis-Schoute, H Akram, T Foltynie… - Biological …, 2019 - Elsevier
Background Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-
compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal …

Individual-specific functional connectivity of the amygdala: A substrate for precision psychiatry

CM Sylvester, Q Yu, AB Srivastava… - Proceedings of the …, 2020 - National Acad Sciences
The amygdala is central to the pathophysiology of many psychiatric illnesses. An imprecise
understanding of how the amygdala fits into the larger network organization of the human …

Obsessive‐compulsive disorder: etiology, neuropathology, and cognitive dysfunction

B Jalal, SR Chamberlain, BJ Sahakian - Brain and behavior, 2023 - Wiley Online Library
Background This review provides an overview of obsessive‐compulsive disorder (OCD)
symptoms, including the four partially distinct subtypes of the disorder, current diagnostic …

Potential optimization of focused ultrasound capsulotomy for obsessive compulsive disorder

J Germann, GJB Elias, C Neudorfer, A Boutet… - Brain, 2021 - academic.oup.com
Obsessive-compulsive disorder is a debilitating and often refractory psychiatric disorder.
Magnetic resonance-guided focused ultrasound is a novel, minimally invasive …

[HTML][HTML] Neuroimaging findings in obsessive–compulsive disorder: A narrative review to elucidate neurobiological underpinnings

N Hazari, JC Narayanaswamy… - Indian journal of …, 2019 - journals.lww.com
Obsessive compulsive disorder (OCD) is a common psychiatric illness and significant
research has been ongoing to understand its neurobiological basis. Neuroimaging studies …

[HTML][HTML] Deep brain stimulation for refractory obsessive-compulsive disorder: towards an individualized approach

S Senova, AH Clair, S Palfi, J Yelnik… - Frontiers in …, 2019 - frontiersin.org
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder featuring repetitive
intrusive thoughts and behaviors associated with a significant handicap. Of patients, 20 …

Exposure and response prevention in the treatment of obsessive-compulsive disorder: current perspectives

C Law, CL Boisseau - Psychology research and behavior …, 2019 - Taylor & Francis
Numerous clinical trials support the efficacy of exposure and response prevention (ERP) for
the treatment of obsessive-compulsive disorder (OCD). Accordingly, ERP has been formally …

Treatment-specific associations between brain activation and symptom reduction in OCD following CBT: a randomized fMRI trial

LJ Norman, KA Mannella, H Yang… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: The authors sought to examine whether brain activity is associated with treatment
response to cognitive-behavioral therapy (CBT) in adolescents and adults with obsessive …