Can epigenetics shine a light on the biological pathways underlying major mental disorders?
L Alameda, G Trotta, H Quigley, V Rodriguez… - Psychological …, 2022 - cambridge.org
A significant proportion of the global burden of disease can be attributed to mental illness.
Despite important advances in identifying risk factors for mental health conditions, the …
Despite important advances in identifying risk factors for mental health conditions, the …
[HTML][HTML] Eating disorders, heredity and environmental activation: getting epigenetic concepts into practice
Epigenetic mechanisms are believed to link environmental exposures to alterations in gene
expression, and in so doing, to provide a physical substrate for the activation of hereditary …
expression, and in so doing, to provide a physical substrate for the activation of hereditary …
[HTML][HTML] Gene variants in eating disorders. Focus on anorexia nervosa, bulimia nervosa, and binge-eating disorder
K Donato, MR Ceccarini, K Dhuli, G Bonetti… - Journal of Preventive …, 2022 - ncbi.nlm.nih.gov
Eating disorders such as anorexia nervosa, bulimia nervosa and binge-eating disorder,
have a deep social impact, concluding with death in cases of severe disease. Eating …
have a deep social impact, concluding with death in cases of severe disease. Eating …
[HTML][HTML] SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits?
Background: The incidence of eating disorders (EDs), serious mental and physical
conditions characterized by a disturbance in eating or eating-related behaviors, has …
conditions characterized by a disturbance in eating or eating-related behaviors, has …
[HTML][HTML] Inclusion of the severe and enduring anorexia nervosa phenotype in genetics research: a scoping review
S Ramsay, K Allison, HS Temples, L Boccuto… - Journal of Eating …, 2024 - Springer
Background Anorexia nervosa has one of the highest mortality rates of all mental illnesses.
For those who survive, less than 70% fully recover, with many going on to develop a more …
For those who survive, less than 70% fully recover, with many going on to develop a more …
[HTML][HTML] Applying epigenetic science to the understanding of eating disorders: A promising paradigm for research and practice
Epigenetic studies in the eating disorders corroborate the idea that eating disorder cause is
multifactorial, and identify markers that could help inform our understanding of illness …
multifactorial, and identify markers that could help inform our understanding of illness …
[HTML][HTML] Brain and gut microbiota disorders in the psychopathology of anorexia nervosa
M Garcia-Gil, MR Ceccarini, F Stoppini… - Translational …, 2022 - degruyter.com
Studies of pathophysiological mechanisms involved in eating disorders (EDs) have
intensified over the past several years, revealing their unprecedented and unanticipated …
intensified over the past several years, revealing their unprecedented and unanticipated …
Acute tryptophan depletion balances altered resting-state functional connectivity of the salience network in female patients recovered from anorexia nervosa
Background: It has been suggested that individuals predisposed to or recovered from
anorexia nervosa experience a hyperserotonergic state associated with anxiety that might …
anorexia nervosa experience a hyperserotonergic state associated with anxiety that might …
[PDF][PDF] Hypermethylation of the serotonin transporter gene and paternal parenting styles in untreated anorexia nervosa patients: A pilot study
Q He, C Lian, S Peng, H Chen, Q Kang, J Chen - Heliyon, 2023 - cell.com
Purpose It has been reported that serotonergic systems and parenting styles are involved in
the pathogenesis of anorexia nervosa (AN). The present study made attempts to examine …
the pathogenesis of anorexia nervosa (AN). The present study made attempts to examine …
Epigenotoxicity: a danger to the future life
F Kefayati, A Karimi Babaahmadi… - … Science and Health …, 2023 - Taylor & Francis
Environmental toxicants can regulate gene expression in the absence of DNA mutations via
epigenetic mechanisms such as DNA methylation, histone modifications, and non-coding …
epigenetic mechanisms such as DNA methylation, histone modifications, and non-coding …