Genomic and neuroimaging approaches to bipolar disorder
MO Kohshour, S Papiol, CRK Ching, TG Schulze - BJPsych open, 2022 - cambridge.org
Background To date, besides genome-wide association studies, a variety of other genetic
analyses (eg polygenic risk scores, whole-exome sequencing and whole-genome …
analyses (eg polygenic risk scores, whole-exome sequencing and whole-genome …
[HTML][HTML] Abnormal patterns of sleep and waking behaviors are accompanied by neocortical oscillation disturbances in an Ank3 mouse model of epilepsy-bipolar …
ANK3 is a leading bipolar disorder (BD) candidate gene in humans and provides a unique
opportunity for studying epilepsy-BD comorbidity. Previous studies showed that deletion of …
opportunity for studying epilepsy-BD comorbidity. Previous studies showed that deletion of …
[HTML][HTML] An investigation of the role of common and rare variants in a large italian multiplex family of multiple sclerosis patients
N Barizzone, R Cagliani, C Basagni, F Clarelli… - Genes, 2021 - mdpi.com
Known multiple sclerosis (MS) susceptibility variants can only explain half of the disease's
estimated heritability, whereas low-frequency and rare variants may partly account for the …
estimated heritability, whereas low-frequency and rare variants may partly account for the …
[HTML][HTML] Temporal changes of gene expression in health, schizophrenia, bipolar disorder, and major depressive disorder
A Arakelyan, S Avagyan, A Kurnosov, T Mkrtchyan… - Schizophrenia, 2024 - nature.com
The molecular events underlying the development, manifestation, and course of
schizophrenia, bipolar disorder, and major depressive disorder span from embryonic life to …
schizophrenia, bipolar disorder, and major depressive disorder span from embryonic life to …
[PDF][PDF] Genetic analysis of a large Han Chinese family line with schizoaffective psychosis
L Zeng, Z He, D Liu, K Li, K Gu, Q Sun, G Mei, Y Zhang… - Heliyon, 2023 - cell.com
To locate the specific susceptibility genes of a high incidence of schizoaffective disease
(SAD) with autonomic dominant inheritance, we recruited a family group from Henan …
(SAD) with autonomic dominant inheritance, we recruited a family group from Henan …
Environmental, genetic and epigenetic contributors to the risk of bipolar disorder
S Hesam Shariati - 2022 - unsworks.unsw.edu.au
Bipolar disorder (BD) is a complex mental illness for which both environmental and
biological (genetic and epigenetic) factors play an aetiological role. This thesis aimed to find …
biological (genetic and epigenetic) factors play an aetiological role. This thesis aimed to find …
Abnormal patterns of sleep and waking behaviors are accompanied by increased slow gamma power in an Ank3 mouse model of epilepsy-bipolar disorder …
ANK3 is a leading bipolar disorder candidate gene in humans. Previous studies showed that
deletion of Ank3-1b, a bipolar disorder (BD)-associated variant of Ank3 in mice leads to …
deletion of Ank3-1b, a bipolar disorder (BD)-associated variant of Ank3 in mice leads to …
disorders) involves the combined actions of hundreds to thousands of genes (Lee et al., 2013). Some families show evidence for important single genes or genetic …
T STUDIES - The Bipolar Brain: Integrating Neuroimaging and …, 2022 - books.google.com
deletions (known as copy number variants), but such families are rare (Ament et al., 2015;
Gershon and Alliey-Rodriguez, 2013). association study (GWAS). A conservative estimate of …
Gershon and Alliey-Rodriguez, 2013). association study (GWAS). A conservative estimate of …
[CITATION][C] Abnormal patterns of sleep and waking behaviors are accompanied by neocortical oscillation disturbances in an Ank3 mouse model of epilepsy-bipolar …
AY Lopez - 2023