The development of neuropsychiatric disorders involves an array of different underlying
mechanisms, many of which remain at the level of hypotheses and thus the centre of much …

Long-term studies of psychiatric illness have been continuing, but the development of the
cause of disease and new treatment methods are slower than the time and cost. Therefore …

While neurons have long been considered the major player in multiple brain functions such
as perception, emotion, and memory, glial cells have been relegated to a far lesser position …

The legacy of the last century of research in psychiatry has been the sophisticated un-
derstanding of the role of neuronal systems in brain function and ultimately in psy …

Microglia, the brain's resident immune cells, are phagocytes of the macrophage lineage that
have a key role in responding to inflammation and immune challenge in the brain. More …

Mental illnesses have long been perceived as the exclusive consequence of abnormalities
in neuronal functioning. Until recently, the role of glial cells in the pathophysiology of mental …

Much of psychiatric neuroscience has focused on studying neurons, with their relative health
or dysfunction considered the key to mental health or disease. There are good reasons for …

For decades, glial cells languished in relative obscurity. Neurones attracted the interest,
kudos and research funding. Here, Mark Greener reports on recent developments in our …

Numerous studies have investigated the causes and mechanisms of psychiatric disorders
through postmortem examination of patients with a history of a schizophrenia, mood …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …