The pathophysiology of schizophrenia and bipolar disorder involves a complex interaction
between genetic and environmental factors that begins in the early stages of …

The etiology of neuropsychiatric disorders, such as schizophrenia and bipolar disorder,
usually involves complex combinations of genetic defects/variations and environmental …

Schizophrenia is one of the leading causes of disability among mental disorders,
contributing to a substantial socioeconomic burden. Our understanding of the mechanisms …

Over a decade of schizophrenia research using human induced pluripotent stem cell (iPSC)-
derived neural models has provided substantial data describing neurobiological …

Schizophrenia and bipolar disorder are complex psychiatric disorders that present unique
challenges in the study of disease biology. There are no objective biological phenotypes for …

Psychiatric disorders are a problem for society both on a micro level involving patients and
their families as well as on a macro level involving global economic costs. For years …

Cellular models of neurodevelopmental disorders provide a valuable experimental system
to uncover disease mechanisms and novel therapeutic strategies. The ability of induced …

The last two decades have seen a revolution in the development of molecular and cellular
neurobiology and improvement of neuroimaging methods. Large-scale genome-wide …

Schizophrenia is a devastating and prevalent psychiatric illness. Progress in understanding
the basic pathophysiological processes underlying this disorder has been hindered by the …

Schizophrenia is a chronic disabling mental disorder that affects about 1% population world-
wide, for which there is a desperate need to develop more effective treatments. In this …