Background: Suicidal behaviours are a major source of mortality and morbidity among
adolescents. Given the maturational changes that occur in cortical and subcortical structures …

Background Growing evidence suggests an endophenotype for suicidality, including brain
morphometric features, could provide an improved platform for suicide risk assessment …

Background Suicide rates among young people have been increasing in recent years, yet
no validated methods are available for identifying those who are at greatest risk for suicide …

Objective: We conducted meta-analyses of functional and structural neuroimaging studies
comparing adolescent and adult individuals with a history of suicidal behavior and a …

Late-onset major depression is thought to have a biological (vascular) basis, which could be
a result of brain structure change. Vascular lesions can affect both the gray matter (GM) and …

Major depressive disorder is a major mental disorder affecting adolescents. Cortical
thickness provides a sensitive measure of age-associated changes. Previous studies using …

Major depressive disorder (MDD) is associated with a considerably increased risk for
suicide. There is evidence to suggest that a predisposition to suicidal behavior may exist …

Identifying brain alterations associated with suicidal thoughts and behaviors (STBs) in young
people is critical to understanding their development and improving early intervention and …

Background: Investigating adolescents and young adults may provide a unique opportunity
to understand developmental aspects of the neurobiology of depression. During …

The extent to which observed differences in emotion processing and regulation neural
circuitry in young adults with current suicidal ideation are paralleled by structural differences …