Background: Alterations in the innate immune/inflammatory system may underlie the
pathophysiology of schizophrenia, but we do not understand the mechanisms involved. The …

Toll like receptors (TLRs), a class of conserved immune molecules are crucially involved in
initiating innate immune response to infection. TLR activation and subsequent inflammation …

Alterations in innate immunity may underlie the pathophysiology of schizophrenia (SZ). Toll-
like receptor-4 (TLR4) is a master element of innate immunity. The specificity proteins (SPs) …

Objective Accumulating evidence suggests alterations of the innate immune system are
related to schizophrenia, although the precise mechanism remains to be elucidated. In this …

Immunological dysregulation has been suggested to be involved in the pathogenesis of
schizophrenia. Accumulating evidences further implicate that activated inflammatory …

Increasing evidence suggests that altered immune functions are related to the
pathophysiology of schizophrenia. Relatively little information is available on Toll-like …

Background: Schizophrenia is highly complex multifactorial psychiatric disorder with poorly
defined etiopathophysiology, which also has manifestations in the immune system. Aims …

Low-grade peripheral inflammation is often present in psychotic patients. Toll-like receptors
(TLRs) are pattern-recognition molecules that initiate inflammation. Our objective was to …

Upregulation of the immune response may be involved in the pathogenesis of schizophrenia
with changes occurring in both peripheral blood and brain tissue. To date, microarray …

Background Schizophrenia is a complex mental disorder marked by severely impaired
thinking, delusional thoughts, hallucinations and poor emotional responsiveness. The …