Background: Bipolar disorder (BD) is a common chronic psychiatric disorder mainly
characterized by episodes of mania, hypomania and depression. The disorder is associated …

Objectives Neuroimaging studies in patients with bipolar disorder (BD) have indicated a
number of structural brain changes, including reduced cortical thickness. However, the …

Background Bipolar disorder (BD) is a highly heritable psychiatric disorder characterized by
episodes of manic and depressed mood states and associated with cortical brain …

Considerable uncertainty exists about the defining brain changes associated with bipolar
disorder (BD). Understanding and quantifying the sources of uncertainty can help generate …

Objectives Bipolar disorder (BD) is a debilitating illness, the psychopathology of which is
associated with aberrant structural and functional differences in the brain. Despite the many …

Background Bipolar disorder (BD) is a debilitating psychiatric disorder affecting millions of
people worldwide with mean time to diagnosis estimated to be at least 10 years. Whilst …

Background Bipolar disorder is thought to be associated with structural brain alterations, but
findings have been inconsistent. Our double meta-analysis investigated the variability and …

Major depressive disorder (MDD) and bipolar disorder (BD) are severe psychiatric diseases
with overlapping symptomatology. Although previous studies reported abnormal brain …

Objective Frontal cortical abnormalities and executive function impairment co‐occur in
bipolar disorder. Recent studies have shown that bipolar subtypes differ in the degree of …

Background Structural brain imaging is assumed to be a key method to elucidate the
underlying neuropathology of bipolar disorder. However, magnetic resonance imaging …