A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21

C Toma, AD Shaw, A Heath, KD Pierce… - Journal of Psychiatry and …, 2021 - jpn.ca
Background Bipolar disorder is a highly heritable psychiatric condition for which specific
genetic factors remain largely unknown. In the present study, we used combined whole …

Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder

TG Schulze, SD Detera-Wadleigh, N Akula… - Molecular …, 2009 - nature.com
Two recent reports have highlighted ANK3 as a susceptibility gene for bipolar disorder (BD).
We first reported association between BD and the ANK3 marker rs9804190 in a genome …

[HTML][HTML] Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations

SD Gonzalez, C Xu, ME Ramirez, JM Zavala… - Translational …, 2013 - nature.com
Over the past several years, genome-wide association studies (GWAS) have successfully
identified genetic loci strongly associated with bipolar disorder (BP). 1–3 Some of the most …

Association of ANK3 with bipolar disorder confirmed in East Asia

A Takata, SH Kim, N Ozaki, N Iwata… - American Journal of …, 2011 - Wiley Online Library
Results of genome‐wide association studies (GWASs) for bipolar disorder (BD) have
indicated ANK3 as one of the most promising candidates for a susceptibility gene. In this …

Re‐sequencing of ankyrin 3 exon 48 and case‐control association analysis of rare variants in bipolar disorder type I

GA Doyle, AT Lai, AD Chou, MJ Wang, X Gai… - Bipolar …, 2012 - Wiley Online Library
Doyle GA, Lai AT, Chou AD, Wang M‐J, Gai X, Rappaport EF, Berrettini WH. Re‐sequencing
of ankyrin 3 exon 48 and case‐control association analysis of rare variants in bipolar …

Genome‐wide association analysis of age at onset and psychotic symptoms in bipolar disorder

P Belmonte Mahon, M Pirooznia… - American Journal of …, 2011 - Wiley Online Library
Genome‐wide association studies (GWAS) have identified several susceptibility loci for
bipolar disorder (BP), most notably ANK3. However, most of the inherited risk for BP remains …

Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case–control samples

M Tesli, P Koefoed, L Athanasiu… - American Journal of …, 2011 - Wiley Online Library
Genetic variants in ankyrin 3 (ANK3) have recently been shown to be associated with
bipolar disorder (BD). We genotyped three ANK3 SNPs previously found to be associated …

[HTML][HTML] Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

W Xu, S Cohen-Woods, Q Chen, A Noor, J Knight… - BMC medical …, 2014 - Springer
Background Recently, genome-wide association studies (GWAS) for cases versus controls
using single nucleotide polymorphism microarray data have shown promising findings for …

[HTML][HTML] Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder

JT Judy, F Seifuddin, M Pirooznia, PB Mahon… - Frontiers in …, 2013 - frontiersin.org
Genome-wide association studies (GWAS) have implicated ANK3 as a susceptibility gene
for bipolar disorder (BP). We examined whether epistasis with ANK3 may contribute to the …

Genome-wide association study of bipolar disorder in European American and African American individuals

EN Smith, CS Bloss, JA Badner, T Barrett… - Molecular …, 2009 - nature.com
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-
wide association (GWA) studies: one involving a sample of individuals of European ancestry …