A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21
Background Bipolar disorder is a highly heritable psychiatric condition for which specific
genetic factors remain largely unknown. In the present study, we used combined whole …
genetic factors remain largely unknown. In the present study, we used combined whole …
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
TG Schulze, SD Detera-Wadleigh, N Akula… - Molecular …, 2009 - nature.com
Two recent reports have highlighted ANK3 as a susceptibility gene for bipolar disorder (BD).
We first reported association between BD and the ANK3 marker rs9804190 in a genome …
We first reported association between BD and the ANK3 marker rs9804190 in a genome …
[HTML][HTML] Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations
Over the past several years, genome-wide association studies (GWAS) have successfully
identified genetic loci strongly associated with bipolar disorder (BP). 1–3 Some of the most …
identified genetic loci strongly associated with bipolar disorder (BP). 1–3 Some of the most …
Association of ANK3 with bipolar disorder confirmed in East Asia
Results of genome‐wide association studies (GWASs) for bipolar disorder (BD) have
indicated ANK3 as one of the most promising candidates for a susceptibility gene. In this …
indicated ANK3 as one of the most promising candidates for a susceptibility gene. In this …
Re‐sequencing of ankyrin 3 exon 48 and case‐control association analysis of rare variants in bipolar disorder type I
Doyle GA, Lai AT, Chou AD, Wang M‐J, Gai X, Rappaport EF, Berrettini WH. Re‐sequencing
of ankyrin 3 exon 48 and case‐control association analysis of rare variants in bipolar …
of ankyrin 3 exon 48 and case‐control association analysis of rare variants in bipolar …
Genome‐wide association analysis of age at onset and psychotic symptoms in bipolar disorder
P Belmonte Mahon, M Pirooznia… - American Journal of …, 2011 - Wiley Online Library
Genome‐wide association studies (GWAS) have identified several susceptibility loci for
bipolar disorder (BP), most notably ANK3. However, most of the inherited risk for BP remains …
bipolar disorder (BP), most notably ANK3. However, most of the inherited risk for BP remains …
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case–control samples
M Tesli, P Koefoed, L Athanasiu… - American Journal of …, 2011 - Wiley Online Library
Genetic variants in ankyrin 3 (ANK3) have recently been shown to be associated with
bipolar disorder (BD). We genotyped three ANK3 SNPs previously found to be associated …
bipolar disorder (BD). We genotyped three ANK3 SNPs previously found to be associated …
[HTML][HTML] Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1
Background Recently, genome-wide association studies (GWAS) for cases versus controls
using single nucleotide polymorphism microarray data have shown promising findings for …
using single nucleotide polymorphism microarray data have shown promising findings for …
[HTML][HTML] Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder
Genome-wide association studies (GWAS) have implicated ANK3 as a susceptibility gene
for bipolar disorder (BP). We examined whether epistasis with ANK3 may contribute to the …
for bipolar disorder (BP). We examined whether epistasis with ANK3 may contribute to the …
Genome-wide association study of bipolar disorder in European American and African American individuals
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-
wide association (GWA) studies: one involving a sample of individuals of European ancestry …
wide association (GWA) studies: one involving a sample of individuals of European ancestry …
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