Background: Dysfunctional reward processing is present in individuals with schizophrenia-
spectrum disorders (SSD) and may confer vulnerability to addiction. Our objective was to …

Deficits in incentive motivation are often present in both Schizophrenia Spectrum Disorders
(SSD) and substance-use disorders. The current study aims to test whether the presence of …

Chronic cannabis use and schizophrenia are both thought to affect reward processing.
While behavioural and neural effects on reward processing have been investigated in both …

Patients with schizophrenia may experience a wide variety of symptoms that can affect their
functioning. In this article, we discuss our finding of high drop-out rate of cannabis users in …

Individuals with mood/anxiety disorders may use cannabis for “self-medication,” ie, to induce
positive mood or attenuate aversive mood states. However, little neurobiological evidence …

Motivational and perceptual disturbances co-occur in psychosis and have been linked to
aberrations in reward learning and sensory gating, respectively. Although traditionally …

Background and Objectives We investigated subjective reasons/motivation for cannabis use
in patients with schizophrenia (n= 51) compared to otherwise healthy cannabis users (n …

Imaging studies of reward processing have demonstrated a mesolimbic-mesocortical
dopaminergic dysfunction in schizophrenia. Such studies on reward processing in patients …

Importance Abnormal reward processing is suggested to underlie the formation of psychotic
symptoms, likely driven by elevated ventral striatal (VS) dopamine levels. Functional …

Objective: Cannabis use is widespread among patients with schizophrenia despite its
negative impact on the course of the disease. Craving is a considerable predictor for relapse …