Background: Structural differences associated with depression have not been confirmed in
brain regions apart from the hippocampus. Comorbid anxiety has been inconsistently …

Medial temporal lobe structures have long been implicated in the pathogenesis of major
depressive disorder. Although findings of smaller hippocampal and amygdalar volumes are …

Context Major depressive disorder (MDD), panic disorder, and social anxiety disorder are
among the most prevalent and frequently co-occurring psychiatric disorders in adults and …

Objectives: The associations between subclinical depressive symptoms, as well specific
symptom subscales, on brain structure in aging are not completely elucidated. This study …

Background Several neuroimaging studies report reduced hippocampal volume in
depressed patients. However, it is still unclear if hippocampal changes in healthy individuals …

Background: Some, although not all, studies report small hippocampal volume in patients
with major depressive disorder (MDD) relative to healthy controls. Here, we explore the …

BackgroundPatients with major depression show reduced hippocampal volume compared
to healthy controls. However, the contribution of patients' cumulative illness severity to …

Background Reduced cortical thickness is a candidate biological marker of depression,
although findings are inconsistent. This could reflect analytic heterogeneity, such as use of …

Introduction The investigation of disease course‐associated brain structural alterations in
Major Depressive Disorder (MDD) have resulted in heterogeneous findings, possibly due to …

BackgroundEvidence for structural hippocampal change in depression is limited despite
reports of neuronal damage due to hypercortisolaemia and vascular pathology. AimsTo …