Background: To date, antidepressant drugs show limited efficacy, leaving a large number of
patients experiencing severe and persistent symptoms of major depression. Previous open …

Background Deep brain stimulation (DBS) of the subcallosal cingulate gyrus (SCG) is an
experimental approach in treatment-resistant depression (TRD). Short-term results of …

Deep brain stimulation (DBS) is currently tested as an experimental therapy for patients with
treatment-resistant depression (TRD). Here we report on the short-and long-term (1 yr) …

BACKGROUND: A preliminary report in six patients suggested that deep brain stimulation
(DBS) of the subcallosal cingulate gyrus (SCG) may provide benefit in treatment-resistant …

Background Deep brain stimulation (DBS) of the subcallosal cingulate gyrus (SCG) is an
experimental approach in treatment-resistant depression (TRD). Apart from its potential long …

Background Deep brain stimulation (DBS) of the subcallosal cingulate white matter has
shown promise as an intervention for patients with chronic, unremitting depression. To test …

Background: Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is reported to
be a safe and effective new treatment for treatment-resistant depression (TRD). However …

Objective: Deep brain stimulation of the subcallosal cingulate (SCC DBS) has been studied
as a potential treatment for severe and refractory major depressive disorder since 2005. The …

Context Deep brain stimulation (DBS) may be an effective intervention for treatment-resistant
depression (TRD), but available data are limited. Objective To assess the efficacy and safety …

Deep brain stimulation (DBS) is being investigated as a therapeutic alternative for patients
with treatment-resistant depression (TRD), but its cognitive safety has been scarcely …