Inhibition of fear is differentially associated with cycling estrogen levels in women

EM Glover, KB Mercer, SD Norrholm, M Davis… - Journal of Psychiatry and …, 2013 - jpn.ca
Background: Although the prevalence of posttraumatic stress disorder (PTSD) is twice as
high in women as it is in men, the role of estrogen in the risk for PTSD is not well understood …

Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder

EM Glover, T Jovanovic, KB Mercer, K Kerley… - Biological …, 2012 - Elsevier
BACKGROUND: Women are twice as likely to develop posttraumatic stress disorder (PTSD)
than men. As shown in our previous work, the inability to suppress fear responses in safe …

Estradiol modulates neural and behavioral arousal in women with posttraumatic stress disorder during a fear learning and extinction task

A Sartin-Tarm, MC Ross, AA Privatsky… - Biological Psychiatry …, 2020 - Elsevier
Background Fear responding in posttraumatic stress disorder (PTSD) is sexually
heterogeneous and varies with hormonal fluctuations throughout the menstrual cycle. While …

Stress exposure prior to fear acquisition interacts with estradiol status to alter recall of fear extinction in humans

MI Antov, U Stockhorst - Psychoneuroendocrinology, 2014 - Elsevier
Classical fear acquisition and extinction are important models for the etiology and treatment
of anxiety disorders such as posttraumatic stress disorder (PTSD). Women are at a higher …

Estrogen, progesterone, and the menstrual cycle: A systematic review of fear learning, intrusive memories, and PTSD

NM Garcia, RS Walker, LA Zoellner - Clinical psychology review, 2018 - Elsevier
Women are disproportionately affected by posttraumatic stress disorder (PTSD), and
gonadal hormones are implicated in fear learning processes associated with PTSD. In …

Estrogen and extinction of fear memories: implications for posttraumatic stress disorder treatment

EM Glover, T Jovanovic, SD Norrholm - Biological psychiatry, 2015 - Elsevier
Posttraumatic stress disorder (PTSD) is a psychiatric illness whose prevalence in women is
more than twice the rate as men. Despite a burgeoning literature characterizing sex …

Contribution of estradiol levels and hormonal contraceptives to sex differences within the fear network during fear conditioning and extinction

MJ Hwang, RG Zsido, H Song, EF Pace-Schott… - BMC psychiatry, 2015 - Springer
Background Findings about sex differences in the field of fear conditioning and fear
extinction have been mixed. At the psychophysiological level, sex differences emerge only …

High endogenous estradiol is associated with enhanced cognitive emotion regulation of physiological conditioned fear responses in women

BM Graham, C Ash, ML Den - Psychoneuroendocrinology, 2017 - Elsevier
The sex hormone estradiol has a modifying role in the underlying neurobiology of cognitive
emotion regulation, although whether estradiol is associated with outcomes of techniques …

Low estradiol levels: a vulnerability factor for the development of posttraumatic stress disorder

K Lebron-Milad, BM Graham… - Biological …, 2012 - biologicalpsychiatryjournal.com
Posttraumatic stress disorder (PTSD) affects millions of people who experience trauma in a
given year and women are twice as likely to develop PTSD (1). Many preclinical and clinical …

[HTML][HTML] Low levels of estradiol are associated with elevated conditioned responding during fear extinction and with intrusive memories in daily life

M Wegerer, H Kerschbaum, J Blechert… - Neurobiology of learning …, 2014 - Elsevier
Posttraumatic stress disorder (PTSD) can be conceptualized as a disorder of emotional
memory showing strong (conditioned) responses to trauma reminders and intrusive …