Objective: Because it has been suggested that agents acting on the γ-aminobutyric acid-A
(GABA A) receptor complex, such as the neuroactive steroid 3α, 5α-tetrahydroprogesterone …

Rationale: The neurosteroid 3α-hydroxy-5α-pregnan-20-one (3α, 5α-THP) has been
previously shown to induce catalepsy in mice that is modified by GABAergic, dopaminergic …

Neuroactive steroids may play a role in the pathophysiology of psychotic disorders, but few
studies examined this issue. We compared serum levels of cortisol, testosterone …

Background Certain metabolites of progesterone such as 3α, 5α-tetrahydroprogesterone
(3α, 5α-THP; allopregnanolone) and 3α, 5β-THP (pregnanolone) are potent, positive …

Background. The present study aimed to compare plasma levels of cortisol, testosterone,
dehydroepiandrosterone (DHEA), and prolactin in patients with schizophrenia and healthy …

A number of preclinical studies suggest that progesterone may play an important role in the
stress response, however, the effects of stress on progesterone in humans has not been …

Animal and human studies have revealed an association between androgens and
aggressive behavior. Schizophrenic patients show aggressive behavior but little is known …

It has been suggested that dysregulation of hormones is associated with schizophrenia
(SCZ). This study aimed to measure the serum levels of progesterone and testosterone in …

Background: The evidence of hypothalamic-pituitary-adrenal axis dysfunction in
schizophrenia has been reviewed in the context of the stress-diathesis model …

OBJECTIVE: Previous studies have shown that neuroactive steroids modulate anxiety and
stress reactivity. However, no data on the possible role of these γ-aminobutyric acidA …