Background: Rett syndrome (RTT), a debilitating neuropsychiatric disorder that begins in
early childhood, is characterized by impairments in the autonomic nervous system that can …

Rett syndrome (RTT) is a rare and severe neurological disorder mainly affecting females,
usually linked to methyl-CpG-binding protein 2 (MECP2) gene mutations. Manifestations of …

Complex neurodevelopmental disorders need multi-disciplinary treatment approaches for
optimal care. The clinical effectiveness of treatments is limited in patients with rare genetic …

Background Rett syndrome is a severe neurodevelopmental disorder associated with
mutations in the MECP2 gene. Irregular breathing patterns and abdominal bloating are …

Background Autonomic dysfunction is common in children with Rett syndrome. They usually
manifest with agitation, persistent screaming, constipation, gastroesophageal reflux …

We have investigated whether brainstem assessment using the NeuroScope could be used
for objective and quantitative monitoring of early development and later progress in Rett …

Rett syndrome is a neurodevelopmental disorder that in most cases is consequent to a
mutation in the MECP2 gene. The central nervous system is the primary organ system …

Incidence of sudden death in Rett syndrome is greater than that of the general population,
and cardiac electrical instability is a prime suspect cause. The objective of the present study …

Rett syndrome is a neurological disorder caused by loss of function of methyl-CpG-binding
protein 2 (MeCP2). Reduced function of this ubiquitous transcriptional regulator has a …

Many studies have attempted to establish the genotype–phenotype correlation in Rett
syndrome (RTT). Cardiorespiratory measurements provide robust objective data, to correlate …