Subcortical volumetric alterations as potential predictors of methylphenidate treatment response in youth with attention-deficit/hyperactivity disorder

JS Kim, KH Lee, CS Hwang, JW Kim - Journal of Psychiatry and …, 2022 - jpn.ca
Background: Patients with attention-deficit/hyperactivity disorder (ADHD) show structural
alterations in the subcortical and dopaminergic regions of the brain. Methylphenidate is a …

Combined stimulant and antipsychotic treatment in adolescents with attention-deficit/hyperactivity disorder: a cross-sectional observational structural MRI study

LJS Schweren, CA Hartman, MP Zwiers… - European child & …, 2015 - Springer
Meta-analyses suggest normalizing effects of methylphenidate on structural fronto-striatal
abnormalities in patients with attention-deficit/hyperactivity disorder (ADHD). A subgroup of …

MR imaging of the effects of methylphenidate on brain structure and function in attention-deficit/hyperactivity disorder

LJS Schweren, P de Zeeuw, S Durston - European …, 2013 - Elsevier
Methylphenidate is the first-choice pharmacological intervention for the treatment of
Attention-Deficit/Hyperactivity Disorder (ADHD). The pharmacological and behavioral effects …

[HTML][HTML] Regional brain volume predicts response to methylphenidate treatment in individuals with ADHD

JC Chang, HY Lin, J Lv, WYI Tseng, SSF Gau - BMC psychiatry, 2021 - Springer
Background Despite the effectiveness of methylphenidate for treating ADHD, up to 30% of
individuals with ADHD show poor responses to methylphenidate. Neuroimaging biomarkers …

Intrinsic brain connectivity following long-term treatment with methylphenidate in children with attention-deficit/hyperactivity disorder

L Battel, RR Kieling, C Kieling, M Anés… - Journal of child and …, 2016 - liebertpub.com
Introduction: Although widely used for the treatment of attention-deficit/hyperactivity disorder
(ADHD) across the life span, the effects of methylphenidate (MPH) on the brain are not …

Striatal volume deficits in children with ADHD who present a poor response to methylphenidate

A Moreno, L Duno, E Hoekzema, M Picado… - European child & …, 2014 - Springer
Methylphenidate (MPH) is the first choice of medical treatment for attention-
deficit/hyperactivity disorder (ADHD). Its mechanism of action is to inhibit the reuptake of …

Methylphenidate effects on cortical thickness in children and adults with attention-deficit/hyperactivity disorder: a randomized clinical trial

KB Walhovd, I Amlien, A Schrantee… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although methylphenidate is frequently used to treat
children with attention-deficit/hyperactivity disorder, it is currently unknown how …

Effects of a single‐dose methylphenidate challenge on resting‐state functional connectivity in stimulant‐treatment naive children and adults with ADHD

A Kaiser, C Broeder, JR Cohen, L Douw… - Human brain …, 2022 - Wiley Online Library
Prior studies suggest that methylphenidate, the primary pharmacological treatment for
attention‐deficit/hyperactivity disorder (ADHD), alters functional brain connectivity. As the …

Age-dependent effects of methylphenidate on the human dopaminergic system in young vs adult patients with attention-deficit/hyperactivity disorder: a randomized …

A Schrantee, HGH Tamminga, C Bouziane… - JAMA …, 2016 - jamanetwork.com
Importance Although numerous children receive methylphenidate hydrochloride for the
treatment of attention-deficit/hyperactivity disorder (ADHD), little is known about age …

Long-term effects of methylphenidate on neural networks associated with executive attention in children with ADHD: results from a longitudinal functional MRI study

K Konrad, S Neufang, GR Fink… - Journal of the American …, 2007 - Elsevier
OBJECTIVE: Little is known about the long-term effects of stimulants on the functional
organization of the developing brain. Nonacute effects of stimulants on neural activity related …