Background: Schizophrenia, bipolar disorder and major depressive disorder are
increasingly being conceptualized as a transdiagnostic continuum. Disruption of white …

Animal data suggest that the gene neuregulin-1 (NRG1) is involved in neuronal myelination.
A haplotype (deCODE) in the 5′ end region of the gene was described to double the risk …

Theories of abnormal anatomical and functional connectivity in schizophrenia and bipolar
disorder are supported by evidence from functional magnetic resonance imaging (MRI) …

Context NRG1is a schizophrenia candidate gene and plays an important role in brain
development and neural function. Schizophrenia is a complex disorder, with etiology likely …

Objective: Genes implicated in schizophrenia are enriched in networks differentially
regulated during human CNS development. Neuregulin 3 (NRG3), a brain-enriched …

Major psychiatric disorders, including schizophrenia, bipolar disorder and substance
addiction, are partly heritable and show a multifactorial pattern of heredity. Although the …

Abstract Background Neuregulin1β1 (NRG1β1) is essential for neuronal migration during
development and for the ongoing neural plasticity underlying cognitive function. This study …

Diminished left frontotemporal connectivity is among the most frequently reported findings in
schizophrenia and there is evidence that altered neuronal myelination may in part account …

Working memory dysfunctions are a prominent feature in schizophrenia. These impairments
have been linked to alterations in prefrontal brain activation with studies reporting hypo-and …

Background: Structural brain abnormalities are already present during the early phases of
psychosis, but factors underlying brain volume changes are still not well understood. The …