Background: Phenotypic heterogeneity and complicated gene–environment interplay in
etiology are among the primary factors that hinder the identification of genetic variants …

We report a genome-wide association study (GWAS) for cocaine dependence (CD) in three
sets of African-and European-American subjects (AAs and EAs, respectively) to identify …

Cocaine dependence is a complex psychiatric disorder that is highly comorbid with other
psychiatric traits. Twin and adoption studies suggest that genetic variants contribute …

Risk for cocaine dependence (CD) is genetically influenced. We recruited a sample of small
nuclear families (528 full and 155 half sibpairs) with at least one subject affected with CD …

Because DSM‐IV cocaine dependence (CD) is heterogeneous, it is not an optimal
phenotype to identify genetic variation contributing to risk for cocaine use and related …

Drug addiction, one of the major health problems worldwide, is characterized by the loss of
control in drug intake, craving, and withdrawal. At the individual level, drugs of abuse …

Cocaine dependence (CD) is a multifactorial disorder, variable in its manifestations, and
heritable. We examined the concurrent validity of homogeneous subgroups of CD as …

We investigated the genetic and molecular architecture of cocaine dependence (CD) and
cocaine use by integrating genome‐/transcriptome‐wide analyses. To prioritize candidates …

We integrated genomic and bioinformatic analyses, using data from the largest genome-
wide association study of cocaine dependence (CD; n= 6546; 82.37% with CD; 57.39 …

Cocaine and opioid dependence are common, complex disorders with high heritability that
commonly co-occur with other substance dependence disorders. Improved insight into the …