Sex steroid–related candidate genes in psychiatric disorders

L Westberg, E Eriksson - Journal of Psychiatry and Neuroscience, 2008 - jpn.ca
Sex steroids readily pass the blood-brain barrier, and receptors for them are abundant in
brain areas important for the regulation of emotions, cognition and behaviour. Animal …

Gonadal hormones and sexual behavior

JD Wilson - Clinical Neuroendocrinology, 1982 - Elsevier
Publisher Summary This chapter discusses whether animal models of sexual behavior are
applicable to the understanding of human sexual behavior. Development of reproductive …

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

R Rupprecht - Psychoneuroendocrinology, 2003 - Elsevier
Steroids influence neuronal function through binding to cognate intracellular receptors
which may act as transcription factors in the regulation of gene expression. In addition …

Effects of estrogens on central nervous system neurotransmission: implications for sex differences in mental disorders

KN Krolick, Q Zhu, H Shi - Progress in molecular biology and translational …, 2018 - Elsevier
Nearly one of every five US individuals aged 12 years old or older lives with certain types of
mental disorders. Men are more likely to use various types of substances, while women tend …

Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology

R Rupprecht, F Di Michele, B Hermann, A Ströhle… - Brain research …, 2001 - Elsevier
Besides their binding to cognate intracellular receptors gonadal steroids may also act as
functional antagonists at the 5-HT3 receptor. A structure–activity relationship for the actions …

[HTML][HTML] Sex steroid hormones in depressive disorders as a basis for new potential treatment strategies

M Pillerová, M Pastorek, V Borbélyová… - Physiological …, 2022 - ncbi.nlm.nih.gov
The sex steroid hormones (SSHs) such as testosterone, estradiol, progesterone, and their
metabolites have important organizational and activational impacts on the brain during …

Sex steroids and human behavior: implications for developmental psychopathology

GM Alexander, BS Peterson - CNS spectrums, 2001 - cambridge.org
In a variety of mammalian species, prenatal androgens organize brain structures and
functions that are later activated by steroid hormones in postnatal life. In humans, studies of …

Polymorphisms in sex steroid receptors: from gene sequence to behavior

DL Maney - Frontiers in neuroendocrinology, 2017 - Elsevier
Sex steroid receptors have received much interest as potential mediators of human
behaviors and mental disorders. Candidate gene association studies have identified about …

The role of sex steroids in forming anxiety states in female mice

AY Galeeva, P Tuohimaa, VG Shalyapina - Neuroscience and behavioral …, 2003 - Springer
Natural fluctuations in sex hormones during the ovarian cycle have enormous influences on
ongoing psychological status in the female body. We report here studies of the effects of …

Sex hormones and neural mechanisms

DL Keefe - Archives of sexual behavior, 2002 - Springer
Sex steroids play important and diverse roles in the regulation of structure and function of
the central nervous system. Early in life, steroids shape the structure of sensitive areas of the …