Background: Transcranial magnetic stimulation can be combined with electromyography
(TMS-EMG) and electroencephalography (TMS-EEG) to evaluate the excitatory and …

Characterizing the neurobiology of schizophrenia and other major psychiatric disorders is
one of the main challenges of the current research in psychiatry. The availability of …

Transcranial magnetic stimulation is an established method to probe inhibitory and
facilitatory networks within the human motor cortex. Reduced motor-cortical inhibition is a …

Schizophrenia (SCZ) is a serious mental disorder, and its pathogenesis is complex.
Recently, the glutamate hypothesis and the excitatory/inhibitory (E/I) imbalance hypothesis …

Transcranial magnetic stimulation (TMS) provides an intriguing in vivo method to investigate
motor cortex excitability in men. This offers new insights into the neurophysiological basis of …

Background: Abnormalities in brain plasticity, possibly related to abnormal cortical inhibition
(CI), have been proposed to underlie the pathophysiology of schizophrenia. Transcranial …

Advances in psychiatric neuroscience have transformed our understanding of impaired and
spared brain functions in psychotic illnesses. Despite substantial progress, few (if any) …

In schizophrenia and related disorders, a deeper mechanistic understanding of neocortical
dysfunction will be essential to developing new diagnostic and therapeutic techniques. To …

Cognitive impairment is highly prevalent in schizophrenia and treatment options are
severely limited. A greater understanding of the pathophysiology of impaired cognition …

Background Several lines of investigations converge upon aberrant synaptic plasticity as a
potential pathophysiological characteristic of schizophrenia. In vivo experiments using …