BDNF protein levels are decreased in transformed lymphoblasts from lithium-responsive patients with bipolar disorder

M Tseng, M Alda, L Xu, X Sun, JF Wang, P Grof… - Journal of Psychiatry and …, 2008 - jpn.ca
Objective: Brain-derived neurotrophic factor (BDNF) is a key factor in neuroplasticity and has
been implicated in the affective disorders; studies have demonstrated elevated BDNF in …

Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: a preliminary 4-week study

RT de Sousa, MT van de Bilt, BS Diniz, RB Ladeira… - Neuroscience …, 2011 - Elsevier
Several studies have suggested an important role for brain-derived neurotrophic factor
(BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms …

Brain-derived neurotrophic factor levels in newly diagnosed patients with bipolar disorder, their unaffected first-degree relatives and healthy controls

NA Petersen, MØ Nielsen, K Coello, S Stanislaus… - BJPsych Open, 2021 - cambridge.org
BackgroundBrain-derived neurotrophic factor (BDNF), which facilitates neuroplasticity and
synaptogenesis, may be decreased in bipolar disorder, but has not been systematically …

Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients

GS de Oliveira, KM Ceresér, BS Fernandes… - Journal of Psychiatric …, 2009 - Elsevier
Bipolar disorder (BD) has been associated with abnormalities in neuroplasticity and
previous studies suggest an important role for BDNF in the pathophysiology of BD. The …

Alterations in BDNF (brain derived neurotrophic factor) and GDNF (glial cell line-derived neurotrophic factor) serum levels in bipolar disorder: the role of lithium

Z Tunca, A Ozerdem, D Ceylan, Y Yalçın, G Can… - Journal of affective …, 2014 - Elsevier
Objective Brain-derived neurotrophic factor (BDNF) has been consistently reported to be
decreased in mania or depression in bipolar disorders. Evidence suggests that Glial cell line …

State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: a meta-analytic study

PY Lin - Neuroscience letters, 2009 - Elsevier
Evidence has suggested a role of brain-derived neurotrophic factor (BDNF) in the
pathogenesis of bipolar disorder (BD). Recent studies have examined BDNF levels in BD …

Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder

F Kapczinski, BN Frey, M Kauer-Sant'Anna… - Expert review of …, 2008 - Taylor & Francis
Initial descriptions of bipolar disorder (BD) emphasized that patients returned to a baseline
condition after acute episodes. Such definitions were operational in teasing bipolar disorder …

Brain‐derived neurotrophic factor (BDNF) gene not associated with antidepressant‐induced mania

G Zai, E Mundo, J Strauss, GWH Wong… - Bipolar …, 2007 - Wiley Online Library
Background: Brain‐derived neurotrophic factor (BDNF) plays an important role in the
regulation of synaptic plasticity and neurotransmitter release across multiple …

Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode

R Machado-Vieira, MO Dietrich, R Leke, VH Cereser… - Biological …, 2007 - Elsevier
BACKGROUND: Bipolar disorder (BD) has been increasingly associated with abnormalities
in neuroplasticity and cellular resilience. Brain Derived Neurotrophic Factor (BDNF) gene …

[HTML][HTML] Brain-derived neurotrophic factor protein and mRNA levels in patients with bipolar mania–A preliminary study

CC Lin, CT Lee, YT Lo, TL Huang - biomedical journal, 2016 - Elsevier
Background Brain-derived neurotrophic factor (BDNF) protein or mRNA levels may be
involved in the pathophysiology of bipolar disorder. However, the results were inconsistent …