Background: The aim of the present study was to map the pathophysiology of resting state
functional connectivity accompanying structural and functional abnormalities in children with …

Accumulating studies demonstrate emotional and cognitive dysregulation in the euthymic
period of pediatric bipolar disorder (PBD). However, the relative contribution of functional …

Mood disorders/psychosis have been associated with dysfunctions in the default mode
network (DMN). However, the relative contributions of DMN regions to state and trait …

Bipolar disorder is characterized by a functional imbalance between hyperactive
ventral/limbic areas and hypoactive dorsal/cognitive brain regions potentially contributing to …

This study examined whether adolescents with pediatric bipolar disorder (PBD) have
abnormal regional functional connectivity in distributed brain networks during an affective …

BACKGROUND:: The recent upsurge in interest about pediatric bipolar disorder (BD) has
spurred the need for greater understanding of its neurobiology. Structural and functional …

BackgroundMajor questions remain regarding the dysfunctional neural circuitry underlying
the pathophysiology of bipolar disorder (BD) in both youths and adults. In both age groups …

It remains unclear the degree to which youths with episodic mania (bipolar disorder; BD) vs.
those with chronic, severe irritability (severe mood dysregulation, SMD) should be placed in …

Background A precision medicine approach to bipolar disorder (BD) requires greater
knowledge of neural mechanisms, especially within the BD phenotype. The present study …

Background This study aimed to identify how the activity of large-scale brain networks differs
between mood states in bipolar disorder. The authors measured spontaneous brain activity …