Background: Several clinical and radiological markers of early neurodevelopmental
deviations have been independently associated with cognitive impairment in patients with …

Cognitive impairment is a common feature of schizophrenia; however, its origin remains
controversial. Neurodevelopmental abnormalities clearly play a role in pre-morbid cognitive …

Schizophrenia is associated with cognitive deficits across all stages of the illness (ie, high
risk, first episode, early and chronic phases). Identifying the underlying neurobiological …

Individuals with schizophrenia present a neuropsychological deficit throughout the course of
the disorder. Few studies have addressed the progression of the deficit since the prodromal …

Schizophrenia is a complex brain disorder associated with numerous etiological factors and
pathophysiological pathways leading to multiple clinical outcomes. Compelling evidence …

BACKGROUND: Childhood neuromotor dysfunction is a risk factor for schizophrenia, a
disorder in which cognitive deficits are prominent. The relationship between early …

Recent research in schizophrenia has demonstrated widespread abnormalities in patients'
brain structure, cognitive function, and physiology. These abnormalities are most probably …

This study evaluated the longitudinal course of neuropsychological deficits in a group of
patients with new or recent onset schizophrenia. Thirty-five inpatients with DSM-III-R …

Despite consensus that schizophrenia is a neurodevelopmental disorder characterized by
cognitive deficits, objective data documenting the course of cognitive development remain …

In contrast to the findings of progressive structural brain changes in adolescence,
longitudinal studies of patients with early onset schizophrenia spectrum disorders (EOS) …