[PDF][PDF] Light up your life: Optogenetics for depression?

PR Albert - Journal of psychiatry & neuroscience: JPN, 2014 - jpn.ca
In the last year, several new studies have shown the potential of optogenetic stimulation to
rapidly modify depression-and anxiety-related behaviours in animal models. Optogenetic …

Psychiatry's age of enlightenment: optogenetics and the discovery of novel targets for the treatment of psychiatric disorders

MM Sidor - Journal of Psychiatry and Neuroscience, 2012 - jpn.ca
A major goal of neuroscience has been to understand the systems-level neural processes
governing higher-order functions, such as perception, cognition and emotion. Until recently …

Shedding light on brain circuits

TR Insel, M Freund - Biological psychiatry, 2012 - biologicalpsychiatryjournal.com
It has been said that scientific progress depends more on new technologies than new
concepts. In truth, it is often new technologies that generate new concepts. For systems …

Optogenetics: A revolutionary approach for the study of depression

M Fakhoury - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
Depression is a severe and chronic mental disorder that affects millions of individuals
worldwide. Symptoms include depressed mood, loss of interest, reduced motivation and …

Optogenetics: what it has uncovered in potential pathways of depression

Z Cheng, R Cui, T Ge, W Yang, B Li - Pharmacological Research, 2020 - Elsevier
Optogenetics is a biological technique, which involves controlling the biological functions of
target cells using light. In recent years, optogenetics has become one of the most advanced …

Illuminating circuitry relevant to psychiatric disorders with optogenetics

EE Steinberg, DJ Christoffel, K Deisseroth… - Current opinion in …, 2015 - Elsevier
Highlights•Optogenetic dissection of disease-relevant neural circuits is accelerating the
pace of preclinical research into the etiology and treatment of mental illness.•Optogenetics …

Optogenetics in psychiatric diseases

C Touriño, A Eban-Rothschild, L de Lecea - Current opinion in …, 2013 - Elsevier
Optogenetic tools have revolutionized the field of neuroscience, and brought the study of
neural circuits to a higher level. Optogenetics has significantly improved our understanding …

Optogenetics and psychiatry: applications, challenges, and opportunities

K Deisseroth - Biological psychiatry, 2012 - biologicalpsychiatryjournal.com
Achieving circuit-level insight into the fundamental nature of psychiatric symptoms has long
proven elusive. Technological limitations have traditionally prevented cell type-targeted and …

A pragmatic reevaluation of the efficacy of nonhuman primate optogenetics for psychiatry

E Bliss-Moreau, VD Costa… - Oxford Open …, 2022 - academic.oup.com
Translational neuroscience is committed to generating discoveries in the laboratory that
ultimately can improve human lives. Optogenetics has received considerable attention …

[HTML][HTML] Advances in optogenetic studies of depressive-like behaviors and underlying neural circuit mechanisms

S Lin, Y Du, Y Xia, Y Xie, L Xiao, G Wang - Frontiers in Psychiatry, 2022 - frontiersin.org
Backgrounds The neural circuit mechanisms underlying depression remain unclear.
Recently optogenetics has gradually gained recognition as a novel technique to regulate the …