Double-blind optimization of subcallosal cingulate deep brain stimulation for treatment-resistant depression: a pilot study

R Ramasubbu, S Anderson, A Haffenden… - Journal of Psychiatry and …, 2013 - jpn.ca
Background: Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is reported to
be a safe and effective new treatment for treatment-resistant depression (TRD). However …

Deep brain stimulation of the subcallosal cingulate gyrus in patients with treatment-resistant depression: a double-blinded randomized controlled study and long-term …

A Merkl, S Aust, GH Schneider… - Journal of affective …, 2018 - Elsevier
Background Deep brain stimulation (DBS) of the subcallosal cingulate gyrus (SCG) is an
experimental approach in treatment-resistant depression (TRD). Short-term results of …

Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial

PE Holtzheimer, MM Husain, SH Lisanby… - The Lancet …, 2017 - thelancet.com
Background Deep brain stimulation (DBS) of the subcallosal cingulate white matter has
shown promise as an intervention for patients with chronic, unremitting depression. To test …

Subcallosal cingulate cortex deep brain stimulation for treatment-resistant depression: a systematic review

M Sobstyl, A Kupryjaniuk, M Prokopienko… - Frontiers in …, 2022 - frontiersin.org
Background Deep brain stimulation (DBS) is considered a relatively new and still
experimental therapeutic modality for treatment-resistant depression (TRD). There is clinical …

Long-term outcomes of subcallosal cingulate deep brain stimulation for treatment-resistant depression

AL Crowell, P Riva-Posse… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Deep brain stimulation of the subcallosal cingulate (SCC DBS) has been studied
as a potential treatment for severe and refractory major depressive disorder since 2005. The …

Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression

PE Holtzheimer, ME Kelley, RE Gross… - Archives of general …, 2012 - jamanetwork.com
Context Deep brain stimulation (DBS) may be an effective intervention for treatment-resistant
depression (TRD), but available data are limited. Objective To assess the efficacy and safety …

Deep brain stimulation of the subcallosal cingulate gyrus: further evidence in treatment-resistant major depression

D Puigdemont, R Pérez-Egea… - International Journal …, 2012 - academic.oup.com
Deep brain stimulation (DBS) is currently tested as an experimental therapy for patients with
treatment-resistant depression (TRD). Here we report on the short-and long-term (1 yr) …

A randomized double-blind crossover trial of deep brain stimulation of the subcallosal cingulate gyrus in patients with treatment-resistant depression: a pilot study of …

D Puigdemont, MJ Portella, R Pérez-Egea… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: To date, antidepressant drugs show limited efficacy, leaving a large number of
patients experiencing severe and persistent symptoms of major depression. Previous open …

Practical considerations in the development and refinement of subcallosal cingulate white matter deep brain stimulation for treatment-resistant depression

P Riva-Posse, PE Holtzheimer, SJ Garlow… - World Neurosurgery, 2013 - Elsevier
Background Deep brain stimulation has been investigated in the past decade as a viable
intervention for treatment-resistant depression. Methods Several anatomic targets have …

Neuropsychological function before and after subcallosal cingulate deep brain stimulation in patients with treatment‐resistant depression

JL Moreines, SM McClintock, ME Kelley… - Depression and …, 2014 - Wiley Online Library
Background Treatment‐resistant depression (TRD) is a pervasive and difficult to treat
condition for which deep brain stimulation (DBS) of the subcallosal cingulate white matter …