Objective: Investigators have reported that weight gain attributed to clozapine is associated
with its clinical response. However, weight gain is a nonspecific physiological variable that …

Metabolic abnormalities are serious health problems in individuals with schizophrenia.
Paradoxically, studies have noted an association where individuals who gained body weight …

Increases in serum triglyceride (TG) levels are associated with clinical response to clozapine
treatment. Clozapine is the most efficacious therapy for treatment of refractory schizophrenia …

Objective This study examined whether clozapine induces more weight gain than
haloperidol and whether weight gain is related to clinical improvement. Method The weight …

Background To investigate the association of clozapine treatment and weight gain, we
studied short-and long-term weight gain, correlation of weight gain with treatment response …

Background: Some, but not all, previous studies have indicated that weight gain is
associated with greater improvement in psychopathology during clozapine treatment …

Objective: The aim of this study was to test whether the initial antipsychotic response to
clozapine is related to subsequent weight change. Method: This study was an 8-year …

OBJECTIVE: To investigate the effects of 12 weeks of clozapine treatment on levels of
cholesterol and related lipids in patients with schizophrenia. DESIGN: Prospective study …

The aim of this study was to evaluate weight gain during clozapine treatment and to
determine the possible relationship between psychiatric improvement and weight gain. 15 …

Possible variables associated with weight gain during clozapine treatment include dosing,
treatment duration, baseline body mass index (BMI), sex, and plasma norclozapine …